Pajares J M, Santander C
Gastroenterology Department, Hospital Universitario de La Princesa, Universidad Autónoma de Madrid, Spain.
J Gastroenterol. 1996 Nov;31 Suppl 9:1-5.
The aim of this study was to investigate the prevalence of Helicobacter pylori infection-associated chronic gastritis in an unselected Spanish population. Between November 1990 and May 1991, consecutive patients referred for upper gastrointestinal endoscopy due to severe upper abdominal complaints were studied. Only patients with chronic gastritis were included. Four biopsy specimens were taken (two for histologic examination, one for a rapid urease test, and one for culture of H. pylori). A total of 3094 patients from 17 Spanish Autonomic Communities 1817 men (58.7%) and 1277 women (41.3%) were studied by endoscopy. The mean age of the patients overall was 51.4 years. Of these 3094 patients, 1642 had symptomatic chronic gastritis. The prevalence of H. pylori infection in chronic gastritis patients in Spain was 85% (pooled data of the three methods above), and there was at a close correlation between severity of gastritis and H. pylori infection.
本研究的目的是调查在未经过挑选的西班牙人群中幽门螺杆菌感染相关慢性胃炎的患病率。在1990年11月至1991年5月期间，对因严重上腹部不适而转诊进行上消化道内镜检查的连续患者进行了研究。仅纳入患有慢性胃炎的患者。采集了四份活检标本（两份用于组织学检查，一份用于快速尿素酶试验，一份用于幽门螺杆菌培养）。对来自西班牙17个自治区的3094例患者进行了内镜检查，其中男性1817例（58.7%），女性1277例（41.3%）。患者的总体平均年龄为51.4岁。在这3094例患者中，1642例患有症状性慢性胃炎。西班牙慢性胃炎患者中幽门螺杆菌感染的患病率为85%（上述三种方法的汇总数据），胃炎严重程度与幽门螺杆菌感染之间存在密切相关性。
