Topp H, Vangala M, Kritzler K, Schöch G
Forschungsinstitut für Kinderernährung, Dortmund, Germany.
Biol Chem Hoppe Seyler. 1995 Nov;376(11):691-4.
Expired ethane is regarded as an indicator of reactive oxygen species induced lipid peroxidation. We investigated whether Wistar rats of different body weights (BW: 78 +/- 6, 121 +/- 12 and 347 +/- 30 g) and hence different metabolic rates per unit weight, expire different amounts of ethane. We found that expired ethane (pmol/100 g BW/min) decreases with increasing BW (8.6 +/- 1.8, 6.3 +/- 1.5 and 2.8 +/- 0.6, respectively). These values aas well as a recently published average value of 1.0 pmol ethane/100 g BW/min for healthy humans (average BW: 78 kg) indicate a positive relationship between lipid peroxidation and metabolic rate.
呼出的乙烷被视为活性氧诱导脂质过氧化的一个指标。我们研究了不同体重(体重:78±6、121±12和347±30克)因而单位体重代谢率不同的Wistar大鼠呼出的乙烷量是否不同。我们发现,呼出的乙烷(皮摩尔/100克体重/分钟)随体重增加而减少(分别为8.6±1.8、6.3±1.5和2.8±0.6)。这些数值以及最近公布的健康人(平均体重:78千克)呼出乙烷的平均值1.0皮摩尔乙烷/100克体重/分钟表明脂质过氧化与代谢率之间呈正相关。