Dumitraşcu D L, Pascu O, Drăghici A, Pop S, Dumitraşcu D, Iacob G
III. Medizinische Klinik, Universität für Medizin und Pharmazie, Cluj-Napoca, Rumänien.
Rom J Intern Med. 1996 Jan-Jun;34(1-2):91-6.
Many patients with liver cirrhosis have dyspeptic complaints. Peptic ulcer, gallstones and oesophagitis are the most common causes of dyspepsia. Functional dyspepsia is infrequently investigated in liver cirrhosis. Sixty-two patients with liver cirrhosis and dyspepsia were submitted to endoscopic and sonographic investigation. In 28 of them no organic finding was detected. These cases were considered as having functional dyspepsia. 36% were of dysmotility-like type, 28% were ulcer- and reflux-like, each, and 7% were of idiopathic type. Aerophagia could not be taken in consideration as functional dyspepsia, due to portal hypertension. In comparison with a group of 30 patients with functional dyspepsia without liver cirrhosis, functional dyspepsia in liver cirrhosis is more frequent in men than in women and occurs about a decade later. In 12 subjects the gastric emptying of a semifluid meal estimated by sonography was normal. Functional dyspepsia is a reality in liver cirrhosis. Gastric emptying seems not to have a major role in the etiopathogenesis of such complaints.
许多肝硬化患者有消化不良症状。消化性溃疡、胆结石和食管炎是消化不良最常见的病因。肝硬化患者中很少对功能性消化不良进行研究。62例肝硬化伴消化不良患者接受了内镜和超声检查。其中28例未发现器质性病变。这些病例被认为患有功能性消化不良。36%为动力障碍样型，28%为溃疡样和反流样型，各占28%，7%为特发性型。由于门静脉高压，吞气症不能被视为功能性消化不良。与30例无肝硬化的功能性消化不良患者相比，肝硬化患者的功能性消化不良男性比女性更常见，且发病时间约晚十年。在12名受试者中，通过超声估计的半流质餐胃排空正常。功能性消化不良在肝硬化中是确实存在的。胃排空似乎在这类症状的病因发病机制中不起主要作用。
