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印度南部某糖尿病中心非胰岛素依赖型糖尿病患者视网膜病变的患病率

Prevalence of retinopathy in non insulin dependent diabetes mellitus at a diabetes centre in southern India.

作者信息

Rema M, Ponnaiya M, Mohan V

机构信息

MV Diabetes Specialities Centre, Royapettah, Madras, India.

出版信息

Diabetes Res Clin Pract. 1996 Sep;34(1):29-36. doi: 10.1016/s0168-8227(96)01327-7.

Abstract

A cohort of 6792 NIDDM patients attending a diabetes centre at Madras in South India was screened using a combination of retinal photography and clinical examination by retinal specialists. A total of 2319 patients (34.1%) had evidence of retinopathy. This included 2090 patients (30.8%) with non-proliferative diabetic retinopathy including 435 patients (6.4%) with maculopathy and 229 patients (3.4%) with proliferative diabetic retinopathy. Multiple logistic regression analyses showed that duration of diabetes, glycosylated haemoglobin, type of treatment (insulin treatment versus non-insulin treatment), systolic and diastolic blood pressures and serum creatinine, showed a positive association with retinopathy while body mass index (BMI) showed an inverse association. The prevalence rates of retinopathy in Southern Indians are comparable to those seen in Europeans. However in view of the high prevalence of diabetes in the Indian sub-continent, diabetic retinopathy could become a formidable challenge in the future.

摘要

在印度南部马德拉斯的一家糖尿病中心,对6792名非胰岛素依赖型糖尿病(NIDDM)患者进行了队列研究,采用视网膜摄影和视网膜专家临床检查相结合的方法进行筛查。共有2319名患者(34.1%)有视网膜病变的证据。这包括2090名(30.8%)患有非增殖性糖尿病视网膜病变的患者,其中435名(6.4%)患有黄斑病变,229名(3.4%)患有增殖性糖尿病视网膜病变。多因素logistic回归分析显示,糖尿病病程、糖化血红蛋白、治疗类型(胰岛素治疗与非胰岛素治疗)、收缩压和舒张压以及血清肌酐与视网膜病变呈正相关,而体重指数(BMI)呈负相关。南印度人的视网膜病变患病率与欧洲人相当。然而,鉴于印度次大陆糖尿病的高患病率,糖尿病视网膜病变在未来可能成为一个巨大的挑战。

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