Brook W J, Diaz-Benjumea F J, Cohen S M
European Molecular Biology Laboratory, Heidelberg, Germany.
Annu Rev Cell Dev Biol. 1996;12:161-80. doi: 10.1146/annurev.cellbio.12.1.161.
Recent studies on the development of the legs and wings of Drosophila have led to the conclusion that insect limb development is controlled by localized pattern organizing centers, analogous to those identified in vertebrate embryos. Genetic analysis has defined the events that lead to the formation of these organizing centers and has led to the identification of gene products that mediate organizer function. The possibility of homology between vertebrate and insect limbs is considered in light of recently reported similarities in patterns of gene expression and function.
最近关于果蝇腿部和翅膀发育的研究得出结论，昆虫肢体发育由局部模式组织中心控制，这类似于在脊椎动物胚胎中发现的那些中心。遗传分析已经确定了导致这些组织中心形成的事件，并导致了介导组织者功能的基因产物的鉴定。鉴于最近报道的基因表达和功能模式的相似性，人们考虑了脊椎动物和昆虫肢体之间存在同源性的可能性。
