Greenfield S P, Wan J
Department of Pediatric Urology, Children's Hospital of Buffalo, State University of New York, Buffalo Medical School 14222, USA.
Pediatr Nephrol. 1996 Dec;10(6):789-94. doi: 10.1007/s004670050218.
The efficacy of both medical and surgical therapy for vesicoureteral reflux (VUR) has been well established. Controversy remains, however, regarding who should be evaluated for the presence of VUR, who should undergo corrective surgery, who should be treated medically and for how long. Medical treatment requires many years of continuous antibiotic prophylaxis, so compliance with therapy is essential. Many children are lost to followup, however, and remain untreated after a medical regimen is started. This large number of untreated children raises issues of the appropriateness of blanket therapeutic recommendations for all children with VUR and challenges the clinician to devise more effective treatment strategies.
医学治疗和手术治疗对膀胱输尿管反流（VUR）的疗效已得到充分证实。然而，关于哪些人应接受VUR检查、哪些人应接受矫正手术、哪些人应接受药物治疗以及治疗多久等问题，仍存在争议。药物治疗需要多年持续的抗生素预防，因此治疗的依从性至关重要。然而，许多儿童失访，在开始药物治疗方案后仍未得到治疗。大量未治疗的儿童引发了对所有VUR儿童一概而论的治疗建议是否恰当的问题，并促使临床医生设计更有效的治疗策略。
