van der Kleij F G, Vecht J, Lamers C B, Masclee A A
Dept. of Gastroenterology-Hepatology, University Hospital Leiden, The Netherlands.
Scand J Gastroenterol. 1996 Dec;31(12):1162-6. doi: 10.3109/00365529609036905.
In patients after gastric surgery it is often difficult to discern symptoms from dumping from other postcibal complaints. Strict criteria for dumping provocation test have not been defined.
The sensitivity and specificity of a dumping provocation using 50 g of glucose orally was assessed in 48 patients after gastric surgery, of whom 19 had a typical history of early dumping and 11 had a history of late dumping. Factors were heart rate, packed cell volume, breath hydrogen excretion, and blood glucose concentration.
An increase in heart rate of > or = 10 beats/min in the 1st h had a sensitivity of 100% and a specificity of 94% in detecting early dumping. An early rise in breath H2 excretion showed a sensitivity of 84% and specificity of 94%. The nadir blood glucose concentration was not a sensitive or specific indicator for late dumping.
Both an increase in heart rate of > or = 10 beats/min and a positive breath hydrogen excretion are sensitive indicators for early dumping. Late dumping is better recognized by the occurrence of subjective symptoms during provocation.
在胃手术后的患者中,常常难以区分倾倒综合征的症状与其他餐后不适。尚未明确倾倒激发试验的严格标准。
对48例胃手术后患者进行了口服50克葡萄糖的倾倒激发试验,其中19例有典型的早期倾倒病史,11例有晚期倾倒病史。观察指标包括心率、红细胞压积、呼气氢排泄量和血糖浓度。
第1小时内心率增加≥10次/分钟对早期倾倒的检测灵敏度为100%,特异度为94%。呼气氢排泄量早期升高的灵敏度为84%,特异度为94%。血糖浓度最低点对晚期倾倒不是一个敏感或特异的指标。
心率增加≥10次/分钟和呼气氢排泄阳性都是早期倾倒的敏感指标。晚期倾倒通过激发试验期间出现主观症状能更好地识别。