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格查尔:白纹伊蚊中Tc1家族的一种转座子。

Quetzal: a transposon of the Tc1 family in the mosquito Anopheles albimanus.

作者信息

Ke Z, Grossman G L, Cornel A J, Collins F H

机构信息

Division of Parasitic Diseases, Centers for Disease Control and Prevention, Chamblee, GA 30341, USA.

出版信息

Genetica. 1996 Oct;98(2):141-7. doi: 10.1007/BF00121362.

Abstract

A member of the Tc1 family of transposable elements has been identified in the Central and South American mosquito Anopheles albimanus. The full-length Quetzal element is 1680 base pairs (bp) in length, possesses 236 bp inverted terminal repeats (ITRs), and has a single open reading frame (ORF) with the potential of encoding a 341-amino-acid (aa) protein that is similar to the transposases of other members of the Tc1 family, particularly elements described from three different Drosophila species. The approximately 10-12 copies per genome of Quetzal are found in the euchromatin of all three chromosomes of A. albimanus. One full-length clone, Que27, appears capable of encoding a complete transposase and may represent a functional copy of this element.

摘要

在中美洲和南美洲的白纹伊蚊中发现了转座元件Tc1家族的一个成员。全长的格查尔元件长度为1680个碱基对(bp),具有236 bp的反向末端重复序列(ITR),并具有一个单一的开放阅读框(ORF),有可能编码一种341个氨基酸(aa)的蛋白质,该蛋白质与Tc1家族其他成员的转座酶相似,特别是来自三种不同果蝇物种的元件。在白纹伊蚊所有三条染色体的常染色质中,每个基因组大约有10 - 12个格查尔元件拷贝。一个全长克隆Que27似乎能够编码完整的转座酶,可能代表该元件的一个功能拷贝。

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