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格查尔:白纹伊蚊中Tc1家族的一种转座子。

Quetzal: a transposon of the Tc1 family in the mosquito Anopheles albimanus.

作者信息

Ke Z, Grossman G L, Cornel A J, Collins F H

机构信息

Division of Parasitic Diseases, Centers for Disease Control and Prevention, Chamblee, GA 30341, USA.

出版信息

Genetica. 1996 Oct;98(2):141-7. doi: 10.1007/BF00121362.

DOI:10.1007/BF00121362
PMID:8976062
Abstract

A member of the Tc1 family of transposable elements has been identified in the Central and South American mosquito Anopheles albimanus. The full-length Quetzal element is 1680 base pairs (bp) in length, possesses 236 bp inverted terminal repeats (ITRs), and has a single open reading frame (ORF) with the potential of encoding a 341-amino-acid (aa) protein that is similar to the transposases of other members of the Tc1 family, particularly elements described from three different Drosophila species. The approximately 10-12 copies per genome of Quetzal are found in the euchromatin of all three chromosomes of A. albimanus. One full-length clone, Que27, appears capable of encoding a complete transposase and may represent a functional copy of this element.

摘要

在中美洲和南美洲的白纹伊蚊中发现了转座元件Tc1家族的一个成员。全长的格查尔元件长度为1680个碱基对(bp),具有236 bp的反向末端重复序列(ITR),并具有一个单一的开放阅读框(ORF),有可能编码一种341个氨基酸(aa)的蛋白质,该蛋白质与Tc1家族其他成员的转座酶相似,特别是来自三种不同果蝇物种的元件。在白纹伊蚊所有三条染色体的常染色质中,每个基因组大约有10 - 12个格查尔元件拷贝。一个全长克隆Que27似乎能够编码完整的转座酶,可能代表该元件的一个功能拷贝。

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本文引用的文献

1
The genomes of most animals have multiple members of the Tc1 family of transposable elements.大多数动物的基因组都有转座元件Tc1家族的多个成员。
Genetica. 1996 Oct;98(2):131-40. doi: 10.1007/BF00121361.
2
Hermes, a functional non-Drosophilid insect gene vector from Musca domestica.赫耳墨斯,一种来自家蝇的功能性非果蝇昆虫基因载体。
Genetics. 1996 Mar;142(3):907-14. doi: 10.1093/genetics/142.3.907.
3
S elements: a family of Tc1-like transposons in the genome of Drosophila melanogaster.S元件:果蝇基因组中一类类似Tc1的转座子家族。
一种在动物中新发现的DD36E转座子家族。
Mob DNA. 2019 Nov 23;10:45. doi: 10.1186/s13100-019-0188-x. eCollection 2019.
4
Transposon tools hopping in vertebrates.转座子工具在脊椎动物中的跳跃
Brief Funct Genomic Proteomic. 2008 Nov;7(6):444-53. doi: 10.1093/bfgp/eln049.
5
Conserved motifs and dynamic aspects of the terminal inverted repeat organization within Bari-like transposons.类Bari转座子内末端反向重复序列组织的保守基序和动态特征。
Mol Genet Genomics. 2008 May;279(5):451-61. doi: 10.1007/s00438-008-0324-7.
6
The genomes of most animals have multiple members of the Tc1 family of transposable elements.大多数动物的基因组都有转座元件Tc1家族的多个成员。
Genetica. 1996 Oct;98(2):131-40. doi: 10.1007/BF00121361.
Genetics. 1995 Dec;141(4):1425-38. doi: 10.1093/genetics/141.4.1425.
4
Transposase is the only nematode protein required for in vitro transposition of Tc1.转座酶是Tc1体外转座所需的唯一线虫蛋白。
Genes Dev. 1996 Mar 15;10(6):755-61. doi: 10.1101/gad.10.6.755.
5
Gene transfer into the medfly, Ceratitis capitata, with a Drosophila hydei transposable element.利用海德氏果蝇转座元件将基因导入地中海实蝇(Ceratitis capitata)。
Science. 1995 Dec 22;270(5244):2002-5. doi: 10.1126/science.270.5244.2002.
6
Characterization of the Caenorhabditis elegans Tc1 transposase in vivo and in vitro.秀丽隐杆线虫Tc1转座酶的体内和体外特性研究
Genes Dev. 1993 Jul;7(7A):1244-53. doi: 10.1101/gad.7.7a.1244.
7
Bari-1, a new transposon-like family in Drosophila melanogaster with a unique heterochromatic organization.Bari-1,果蝇中一个新的类转座子家族,具有独特的异染色质组织。
Genetics. 1993 Feb;133(2):335-45. doi: 10.1093/genetics/133.2.335.
8
A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common "D35E" motif.转座酶基因的一个拟议超家族:纤毛原生动物中的类转座子元件及一个常见的“D35E”基序
Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):942-6. doi: 10.1073/pnas.91.3.942.
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10
A technique for nucleic acid in situ hybridization to polytene chromosomes of mosquitoes in the Anopheles gambiae complex.
Insect Mol Biol. 1994 Feb;3(1):41-7. doi: 10.1111/j.1365-2583.1994.tb00149.x.