Pharoah P O, Platt M J, Cooke T
Department of Public Health, University of Liverpool.
Arch Dis Child Fetal Neonatal Ed. 1996 Nov;75(3):F169-73. doi: 10.1136/fn.75.3.f169.
To determine the prevalence of cerebral palsy in a specific population.
Multiple sources of ascertainment were used to create and maintain a register of all cases of cerebral palsy born to mothers resident in the counties of Merseyside and Cheshire in the years 1966 to 1989. Denominator data of infant births and deaths from 1966 to 1981 were obtained from statutory notifications made to health authorities and, for the period 1982-89, from statutory birth and death registrations. Over 1500 cases formed the database for the study.
The prevalence of cerebral palsy has increased among all the low birthweight groups with, most recently, an increase in infants weighing < 1000 g at birth. Low birthweight infants now comprise about 50% of all cases of cerebral palsy; in the early years of the study they comprised about 32% of all cases. The proportion of cerebral palsy by clinical type has changed among low birthweight babies, with relatively fewer cases with diplegia and a concomitant increase in the proportion with hemiplegia. An increase in the severity of functional disability, determined by the proportion of children with severe learning, manual, and ambulatory disabilities, was also found.
The change in the epidemiology of cerebral palsy has implications for the aetiology of the condition, and for health, educational, and social service provision.
确定特定人群中脑瘫的患病率。
采用多种确诊来源，建立并维护一份1966年至1989年期间居住在默西塞德郡和柴郡的母亲所生的所有脑瘫病例登记册。1966年至1981年的婴儿出生和死亡分母数据来自向卫生当局提交的法定通知，1982 - 89年期间的数据来自法定出生和死亡登记。超过1500个病例构成了该研究的数据库。
所有低体重组中脑瘫的患病率均有所上升，最近，出生体重<1000克的婴儿患病率有所增加。低体重婴儿现在约占所有脑瘫病例的50%；在研究早期，他们约占所有病例的32%。低体重婴儿中按临床类型划分的脑瘫比例发生了变化，双瘫病例相对减少，偏瘫比例相应增加。还发现，由严重学习、手部和行走障碍儿童的比例所确定的功能残疾严重程度有所增加。
脑瘫流行病学的变化对该病的病因以及健康、教育和社会服务的提供都有影响。
