Evans T G, Ranson M K, Kyaw T A, Ko C K
Harvard Center for Population and Development Studies, Cambridge, MA 02138, USA.
Br J Ophthalmol. 1996 Oct;80(10):880-9. doi: 10.1136/bjo.80.10.880.
AIMS/BACKGROUND: This paper reports on the findings of a cost and effectiveness study of the trachoma control programme (TCP) in Burma. The TCP began in 1964 employing non-surgical interventions (community education and mass treatment with topical antibiotics) and surgical correction of trichiasis.
Fixed and variable costs of the TCP are assessed over 30 years (1964-93) and apportioned to either surgical or non-surgical interventions. The change in the prevalence of trachoma blindness during this period is used to calculate cases of visual impairment prevented by the TCP. The years of life saved because of premature mortality averted and from living in a handicapped state are added to yield a single measure of utility called handicap adjusted life years (HALYs).
The cost effectiveness of the TCP is $54 per case of visual impairment prevented: $193 and $47 for surgical and non-surgical interventions respectively. The cost utility of the TCP is $4 per HALY averted: $10 and $3 for surgical and non-surgical interventions respectively. Results are highly sensitive to the 1965 prevalence of blindness, the choice of discount rate, and the effectiveness of both interventions.
Thirty years of trachoma control in Burma are associated with a remarkable decline in trachomatous blindness. Both surgical and non-surgical interventions are cost effective means of preventing trachomatous visual impairment. Discussion focuses on methodological limitations and implications for research and policy.
目的/背景:本文报告了缅甸沙眼控制项目(TCP)成本效益研究的结果。TCP始于1964年,采用非手术干预措施(社区教育和局部抗生素群体治疗)以及倒睫的手术矫正。
评估了TCP在30年(1964 - 1993年)期间的固定成本和可变成本,并将其分摊到手术或非手术干预措施中。利用这一时期沙眼性盲患病率的变化来计算TCP预防的视力损害病例数。将因避免过早死亡和避免处于残疾状态而节省的生命年数相加,得出一种称为残疾调整生命年(HALYs)的单一效用衡量指标。
TCP预防每例视力损害的成本效益为54美元:手术和非手术干预措施分别为193美元和47美元。TCP的成本效用为每避免一个HALY 4美元:手术和非手术干预措施分别为10美元和3美元。结果对1965年的盲患病率、贴现率的选择以及两种干预措施的效果高度敏感。
缅甸30年的沙眼控制与沙眼性盲的显著下降相关。手术和非手术干预措施都是预防沙眼性视力损害的具有成本效益的手段。讨论集中在方法学局限性以及对研究和政策的影响。