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使用人工神经网络自动检测糖尿病视网膜病变:一种筛查工具。

Automatic detection of diabetic retinopathy using an artificial neural network: a screening tool.

作者信息

Gardner G G, Keating D, Williamson T H, Elliott A T

机构信息

Department of Clinical Physics and Bio-Engineering, Tennent Institute of Ophthalmology, Glasgow.

出版信息

Br J Ophthalmol. 1996 Nov;80(11):940-4. doi: 10.1136/bjo.80.11.940.

Abstract

AIMS

To determine if neural networks can detect diabetic features in fundus images and compare the network against an ophthalmologist screening a set of fundus images.

METHODS

147 diabetic and 32 normal images were captured from a fundus camera, stored on computer, and analysed using a back propagation neural network. The network was trained to recognise features in the retinal image. The effects of digital filtering techniques and different network variables were assessed. 200 diabetic and 101 normal images were then randomised and used to evaluate the network's performance for the detection of diabetic retinopathy against an ophthalmologist.

RESULTS

Detection rates for the recognition of vessels, exudates, and haemorrhages were 91.7%, 93.1%, and 73.8% respectively. When compared with the results of the ophthalmologist, the network achieved a sensitivity of 88.4% and a specificity of 83.5% for the detection of diabetic retinopathy.

CONCLUSIONS

Detection of vessels, exudates, and haemorrhages was possible, with success rates dependent upon preprocessing and the number of images used in training. When compared with the ophthalmologist, the network achieved good accuracy for the detection of diabetic retinopathy. The system could be used as an aid to the screening of diabetic patients for retinopathy.

摘要

目的

确定神经网络能否检测眼底图像中的糖尿病特征,并将该网络与筛查一组眼底图像的眼科医生进行比较。

方法

从眼底相机采集147张糖尿病患者图像和32张正常图像,存储在计算机上,并使用反向传播神经网络进行分析。该网络经过训练以识别视网膜图像中的特征。评估了数字滤波技术和不同网络变量的效果。然后将200张糖尿病患者图像和101张正常图像随机分组,用于评估该网络相对于眼科医生检测糖尿病视网膜病变的性能。

结果

血管、渗出物和出血的识别检出率分别为91.7%、93.1%和73.8%。与眼科医生的结果相比,该网络检测糖尿病视网膜病变的灵敏度为88.4%,特异度为83.5%。

结论

能够检测血管、渗出物和出血,成功率取决于预处理和训练中使用的图像数量。与眼科医生相比,该网络检测糖尿病视网膜病变具有良好的准确性。该系统可作为筛查糖尿病患者视网膜病变的辅助工具。

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