Madge S, Elford J, Lipman M C, Mintz J, Johnson M A
Department of Thoracic Medicine, Royal Free Hospital School of Medicine, Hampstead, London.
Genitourin Med. 1996 Oct;72(5):347-51. doi: 10.1136/sti.72.5.347.
To estimate the prevalence of sexually transmitted diseases (STDs) and the acceptability of STD screening among people seeking an HIV antibody test in an established free standing HIV testing clinic.
A 9 month period prevalence study conducted between August 1993 and April 1994.
The Same Day Testing Clinic (SDTC) for HIV antibodies at the Royal Free Hampstead NHS Trust Hospital, London.
242 males and 160 females attending the Same Day Testing Clinic.
The prevalence of STDs including gonorrhoea, chlamydia, syphilis and hepatitis B and the percentage of clinic attenders accepting an STD screen.
Of those invited to take part in the study 69% of the males (242/350) and 59% (160/269) of the females agreed to be screened although for a variety of reasons not everyone agreed to a full screen. Two cases of untreated syphilis, no cases of gonorrhoea and six cases of chlamydia were detected. Four people had active, previously undiagnosed herpes while three had genital warts. Evidence of previously unknown hepatitis B infection was found in 26 people. Despite a high level of previous contact with genitourinary medicine services, uptake of hepatitis B vaccination among those homosexual men eligible for immunisation was low (28%; 23/83). Nine (4%) of the males, but none of the females screened for STD were found to be HIV antibody positive.
Among people seeking an HIV antibody test in an established free standing HIV testing clinic, the prevalence of acute STDs was low. However, evidence of previously undiagnosed hepatitis B infection was found in a number of subjects and uptake of vaccination among those most at risk had been low. While opportunistic screening for STD was acceptable to almost two thirds of HIV testing clinic attenders, a substantial minority nonetheless declined this offer. Selective STD screening could be offered to those people seeking an HIV test who report never having been screened before, as both cases of positive syphilis serology and all those of chlamydia were in people who had not previously been screened. All those at risk for hepatitis B infection should be encouraged to establish their infection status and be immunised where appropriate.
评估在一家独立的成熟艾滋病病毒检测诊所中,寻求艾滋病病毒抗体检测的人群中性传播疾病(STD)的患病率以及STD筛查的可接受性。
1993年8月至1994年4月进行的为期9个月的患病率研究。
伦敦皇家自由汉普斯特德国民保健服务信托医院的当日艾滋病病毒抗体检测诊所。
242名男性和160名女性前往当日检测诊所就诊。
包括淋病、衣原体感染、梅毒和乙型肝炎在内的性传播疾病的患病率,以及接受STD筛查的就诊者百分比。
在受邀参加研究的人群中,69%的男性(242/350)和59%的女性(160/269)同意接受筛查,不过由于各种原因,并非所有人都同意进行全面筛查。检测出2例未经治疗的梅毒病例,未检测到淋病病例,6例衣原体感染病例。4人患有活动性、此前未确诊的疱疹,3人患有尖锐湿疣。在26人中发现了此前未知的乙型肝炎感染证据。尽管此前与泌尿生殖医学服务机构有过大量接触,但符合免疫条件的同性恋男性中乙型肝炎疫苗接种率较低(28%;23/83)。接受STD筛查的男性中有9人(4%)被发现艾滋病病毒抗体呈阳性,但女性中无一例呈阳性。
在一家独立的成熟艾滋病病毒检测诊所中,寻求艾滋病病毒抗体检测的人群中急性性传播疾病的患病率较低。然而,在一些受试者中发现了此前未确诊的乙型肝炎感染证据,且高危人群中的疫苗接种率较低。虽然机会性STD筛查为近三分之二的艾滋病病毒检测诊所就诊者所接受,但仍有相当一部分人拒绝了这一提议。对于那些寻求艾滋病病毒检测且报告此前从未接受过筛查的人,可以提供选择性STD筛查,因为梅毒血清学阳性病例和所有衣原体感染病例均出现在此前未接受过筛查的人群中。应鼓励所有乙型肝炎感染风险人群确定其感染状况,并在适当情况下进行免疫接种。