潮湿、霉菌、成人呼吸道症状、哮喘和鼻炎的发作和缓解。
Dampness, mould, onset and remission of adult respiratory symptoms, asthma and rhinitis.
机构信息
Dept of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
These authors contributed equally to this work.
出版信息
Eur Respir J. 2019 May 23;53(5). doi: 10.1183/13993003.01921-2018. Print 2019 May.
STUDY QUESTION
Is dampness and indoor mould associated with onset and remission of respiratory symptoms, asthma and rhinitis among adults?
MATERIALS AND METHODS
Associations between dampness, mould and mould odour at home and at work and respiratory health were investigated in a cohort of 11 506 adults from Iceland, Norway, Sweden, Denmark and Estonia. They answered a questionnaire at baseline and 10 years later, with questions on respiratory health, home and work environment.
RESULTS
Baseline water damage, floor dampness, mould and mould odour at home were associated with onset of respiratory symptoms and asthma (OR 1.23-2.24). Dampness at home during follow-up was associated with onset of respiratory symptoms, asthma and rhinitis (OR 1.21-1.52). Dampness at work during follow-up was associated with onset of respiratory symptoms, asthma and rhinitis (OR 1.31-1.50). Combined dampness at home and at work increased the risk of onset of respiratory symptoms and rhinitis. Dampness and mould at home and at work decreased remission of respiratory symptoms and rhinitis.
THE ANSWER TO THE QUESTION
Dampness and mould at home and at work can increase onset of respiratory symptoms, asthma and rhinitis, and decrease remission.
研究问题
潮湿和室内霉菌与成年人呼吸道症状、哮喘和鼻炎的发作和缓解有关吗？
材料和方法
在冰岛、挪威、瑞典、丹麦和爱沙尼亚的 11506 名成年人队列中，研究了家庭和工作场所的潮湿、霉菌和霉菌气味与呼吸道健康之间的关联。他们在基线和 10 年后回答了一份关于呼吸道健康、家庭和工作环境的问卷。
结果
基线时家中的水损害、地板潮湿、霉菌和霉菌气味与呼吸道症状和哮喘的发作有关（OR 1.23-2.24）。随访期间家中的潮湿与呼吸道症状、哮喘和鼻炎的发作有关（OR 1.21-1.52）。随访期间工作场所的潮湿与呼吸道症状、哮喘和鼻炎的发作有关（OR 1.31-1.50）。家庭和工作场所同时存在潮湿增加了呼吸道症状和鼻炎发作的风险。家庭和工作场所的潮湿和霉菌会降低呼吸道症状和鼻炎的缓解率。
问题的答案
家庭和工作场所的潮湿和霉菌会增加呼吸道症状、哮喘和鼻炎的发作风险，并降低其缓解率。
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