Wilensky J T, Chen T C
Department of Ophthalmology and Visual Sciences, University of Illinois, Chicago Eye and Ear Infirmary, USA.
Trans Am Ophthalmol Soc. 1996;94:147-59; discussion 160-4. doi: 10.1016/s0002-9394(14)70163-1.
A number of published case series provide short-term and intermediate success rates for the surgical treatment of glaucoma with trabeculectomy. There is little information, however, regarding long-term outcomes that extend beyond 10 years. Therefore, we conducted a retrospective study to determine the long-term outcome of eyes that had successful trabeculectomy surgery at 1 year (IOP < 21 mmHg, or lowering by 33% if preoperative IOP was < 21 mm Hg) and had been followed up for at least 10 years. We found 40 such eyes. With respect to IOP control, 83% were still considered to be successful at 5 years, 73% at 10 years, but only 42% at 15 years. Ten percent required additional glaucoma surgery by 5 years, 25% by 10 years, and 58% by 15 years. Forty percent of the eyes had cataract surgery by the time of the last follow-up examination. It appears that there is a significant late failure rate of trabeculectomy in eyes that were initially successful.
一些已发表的病例系列提供了小梁切除术治疗青光眼的短期和中期成功率。然而，关于超过10年的长期结果的信息很少。因此，我们进行了一项回顾性研究，以确定在1年时小梁切除术成功（眼压<21 mmHg，或如果术前眼压<21 mmHg则降低33%）且至少随访10年的眼睛的长期结果。我们找到了40只这样的眼睛。在眼压控制方面，5年时83%仍被认为成功，10年时为73%，但15年时仅为42%。到5年时，10%的患者需要额外的青光眼手术，10年时为25%，15年时为58%。到最后一次随访检查时，40%的眼睛接受了白内障手术。最初成功的眼睛小梁切除术似乎存在显著的晚期失败率。
