卡帕拉三烯，一种从卡帕拉皮樟中提取的活性倍半萜烃。
Caparratriene, an active sesquiterpene hydrocarbon from Ocotea caparrapi.
作者信息
Palomino E, Maldonado C, Kempff M B, Ksebati M B
机构信息
Walker Cancer Research Institute, Detroit, Michigan 48201, USA.
出版信息
J Nat Prod. 1996 Jan;59(1):77-9. doi: 10.1021/np960012r.
PMID:8984157
Abstract
Caparratriene (1), a new sesquiterpene hydrocarbon with significant growth inhibitory activity (IC50 = 3.0 +/- 0.5 x 10(-6) M) against CEM leukemia cells, was isolated from the oil of Ocotea caparrapi (Nates) Dugand. The structure of 1, determined by spectroscopic techniques, corresponded to (E,E)-3,7,11-trimethyl-2,4,10-dodecatriene (C15H26).
摘要
从卡帕拉皮樟（Ocotea caparrapi (Nates) Dugand）的油中分离出了卡帕三烯（1），它是一种新的倍半萜烃，对CEM白血病细胞具有显著的生长抑制活性（IC50 = 3.0 +/- 0.5 x 10(-6) M）。通过光谱技术确定的1的结构为（E,E）-3,7,11-三甲基-2,4,10-十二碳三烯（C15H26）。
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