Rositto A, Molinaro L, Larralde M, Ranalletta M, Drut R
Department of Dermatology, Hospital de Niños, Superiora Sor Maria Ludovica, La Plata, Argentina.
Pediatr Dermatol. 1996 Nov-Dec;13(6):451-4. doi: 10.1111/j.1525-1470.1996.tb00723.x.
We present nine infants (3 to 10 months of age) with numerous small, papular, papular-lichenoid, and papulo-pustular lesions predominantly on the upper and lower limbs associated with local (axillary) lymphadenopathy which appeared after BCG vaccination. Histopathology of the lesions showed small tuberculoid granulomas mainly in the papillary dermis. The presence of BCG bacillus was demonstrated in five out of seven samples from the lymph nodes after culture and in one skin biopsy specimen. All cases, whether treated or not, evolved to complete resolution of the skin lesions. We believe that this peculiar association results from hematogenous spread of the bacillus, which regresses after an adequate immune system reaction.
我们报告了9名年龄在3至10个月的婴儿，他们在卡介苗接种后，上肢和下肢出现了许多小丘疹、丘疹样苔藓样和丘疹脓疱样病变，伴有局部（腋窝）淋巴结肿大。病变的组织病理学显示，主要在乳头真皮层有小结核样肉芽肿。7份淋巴结样本中的5份以及1份皮肤活检标本经培养后证实存在卡介苗杆菌。所有病例，无论是否接受治疗，皮肤病变均完全消退。我们认为，这种特殊关联是由杆菌的血行播散引起的，在免疫系统产生充分反应后，杆菌会消退。
