铝对大鼠肝脏超氧化物歧化酶、过氧化氢酶及脂质过氧化的影响。
Effect of aluminum on superoxide dismutase, catalase and lipid peroxidation of rat liver.
作者信息
Chainy G B, Samanta L, Rout N B
机构信息
Department of Zoology, Utkal University, Bhubaneswar, India.
出版信息
Res Commun Mol Pathol Pharmacol. 1996 Nov;94(2):217-20.
PMID:8987119
Abstract
Results of the present study suggest that aluminum treatment to rats resulted in elevation of microsomal lipid peroxidation along with inhibition of catalase activity in the liver. Aluminum treatment to rats has no significant effect on rat liver superoxide dismutase activity. A 25% inhibition in catalase activity was observed when liver supernatant was incubated with A1C13 at 5 x 10(-3) M concentration and above.
摘要
本研究结果表明，对大鼠进行铝处理会导致微粒体脂质过氧化增加，同时肝脏中的过氧化氢酶活性受到抑制。对大鼠进行铝处理对大鼠肝脏超氧化物歧化酶活性没有显著影响。当肝脏上清液与浓度为5×10（-3）M及以上的AlC13孵育时，观察到过氧化氢酶活性有25%的抑制。
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