Glasgow R E, Mulvihill S J
Department of Surgery, University of California, San Francisco (UCSF), Medical Center 94143-0788, USA.
West J Med. 1996 Nov;165(5):294-300.
Surgical resection is the only possibly curative treatment of malignant pancreatic neoplasms, but major pancreatic resection for cancer is associated with high rates of morbidity and mortality. The objective of this study was to determine the relation between hospital volume and outcome in patients undergoing pancreatic resection for malignancy in California. Data were obtained from reports submitted to the Office of Statewide Health Planning and Development by all California hospitals from 1990 through 1994. Patient abstracts were analyzed for each of 1,705 patients who underwent major pancreatic resection for malignancy. Of the 298 reporting hospitals, 88% treated fewer than 2 patients per year; these low-volume centers treated the majority of patients. High-volume providers had significantly decreased operative mortality, complication-associated mortality, patient resource use, and total charges and were more likely than low-volume centers to discharge patients to home. These differences were not accounted for by patient mix. This study supports the concept of regionalizing high risk procedures in general surgery, such as major pancreatic resection for cancer.
手术切除是恶性胰腺肿瘤唯一可能治愈的治疗方法,但胰腺癌的大型胰腺切除与高发病率和死亡率相关。本研究的目的是确定加利福尼亚州接受胰腺癌手术切除患者的医院手术量与预后之间的关系。数据来自1990年至1994年加利福尼亚州所有医院提交给全州卫生规划与发展办公室的报告。对1705例接受恶性肿瘤大型胰腺切除的患者的病历摘要进行了分析。在298家报告医院中,88%的医院每年治疗的患者少于2例;这些低手术量中心治疗了大多数患者。高手术量的医疗机构手术死亡率、并发症相关死亡率、患者资源使用和总费用显著降低,并且与低手术量中心相比,更有可能让患者出院回家。这些差异不能用患者构成来解释。本研究支持在普通外科将高风险手术(如胰腺癌大型胰腺切除)进行区域化的概念。