Fornara P, Doehn C, Fricke L, Durek C, Thyssen G, Jocham D
Department of Urology, Medical University of Lübeck, Germany.
J Urol. 1997 Feb;157(2):445-9. doi: 10.1016/s0022-5347(01)65166-8.
We report our experience with bilateral laparoscopic nephrectomy after renal transplantation.
Between August 1994 and October 1995, 11 patients who had previously undergone renal transplantation underwent bilateral laparoscopic nephrectomy at our hospital due to poorly controlled hypertension. The records of 10 patients undergoing bilateral open nephrectomy were reviewed for comparison.
Mean operative time in the laparoscopy group was 195 minutes (range 125 to 270). Mean blood loss was 345 ml. and 1 patient required conversion to an open operation. Oral intake and mobilization were begun 1 day postoperatively. Mean postoperative morphine equivalent consumption was 14 mg., mean hospital stay was 4.2 days (range 3 to 6) and mean return to normal activities was 14 days. At a mean followup of 10.4 months blood pressure had improved significantly in 8 patients (73%). Mean operative time in the open surgery group was 145 minutes (range 115 to 170) and mean postoperative morphine equivalent required was 44 mg. Compared to the laparoscopy group the interval to resumption of oral intake (3.5 days), duration of hospital stay (10.7 days) and return to normal activities (36 days) were prolonged in the open surgery group.
According to our results, bilateral laparoscopic nephrectomy could be an effective alternative for the treatment of severe hypertension after renal transplantation. Compared to open nephrectomy most patients benefit from the laparoscopic approach.
我们报告肾移植后双侧腹腔镜肾切除术的经验。
1994年8月至1995年10月,我院对11例既往接受过肾移植的患者因高血压控制不佳行双侧腹腔镜肾切除术。回顾了10例行双侧开放性肾切除术患者的记录以作比较。
腹腔镜组平均手术时间为195分钟(范围125至270分钟)。平均失血量为345毫升,1例患者需要转为开放手术。术后第1天开始经口进食和活动。术后平均吗啡等效用量为14毫克,平均住院时间为4.2天(范围3至6天),平均恢复正常活动时间为14天。平均随访10.4个月时,8例患者(73%)血压明显改善。开放手术组平均手术时间为145分钟(范围115至170分钟),术后平均吗啡等效用量为44毫克。与腹腔镜组相比,开放手术组经口进食恢复间隔时间(3.5天)、住院时间(10.7天)和恢复正常活动时间(36天)均延长。
根据我们的结果,双侧腹腔镜肾切除术可能是治疗肾移植后严重高血压的一种有效替代方法。与开放性肾切除术相比,大多数患者从腹腔镜手术方法中获益。