Kokic N Z, Adanja J B, Vlajinac D H, Marinkovic P J, Colovic B R, Jarebinski S M
Health Center, Belgrade, Yugoslavia.
Neoplasma. 1996;43(5):353-6.
Case-control study comprised 100 pancreatic cancer patients and the same number of hospital controls individually matched with cases by sex, age and place of residence. According to logistic regression analysis following factors were found to be risk factors for pancreatic cancer: smoking 26 or more cigarettes per day (OR = 43.95, 95% CI = 7.69-192.53), consumption of 5 or more glasses of hard drinks per week (OR = 12.84, 95% CI = 2.13-77.29), coffee consumption during a period exceeding 35 years (OR = 2.50, 95% CI = 1.18-5.28), gall bladder disease in personal history (OR = 4.29, 95% CI = 1.08-16.99) and family history positive on peptic ulcer (OR = 11.71, 95% CI = 0.99-137.98). Two factors appeared to be protective for cancer of pancreas: appendectomy (OR = 0.22, 95% CI = 0.07-0.68) and blood type 0, Rh+ (OR = 0.25, 95% CI = 0.09-0.61).
病例对照研究包括100名胰腺癌患者以及相同数量的医院对照，对照按性别、年龄和居住地点与病例个体匹配。根据逻辑回归分析，发现以下因素是胰腺癌的危险因素：每天吸烟26支或更多（比值比=43.95，95%置信区间=7.69-192.53）、每周饮用5杯或更多杯烈性酒（比值比=12.84，95%置信区间=2.13-77.29）、咖啡饮用超过35年（比值比=2.50，95%置信区间=1.18-5.28）、个人病史中有胆囊疾病（比值比=4.29，95%置信区间=1.08-16.99）以及消化性溃疡家族史呈阳性（比值比=11.71，95%置信区间=0.99-137.98）。有两个因素似乎对胰腺癌有保护作用：阑尾切除术（比值比=0.22，95%置信区间=0.07-0.68）和血型为O型、Rh阳性（比值比=0.25，95%置信区间=0.09-0.61）。
