新生儿甲状腺毒症

Neonatal thyrotoxicosis.

作者信息

Petersen S, Serup J

出版信息

Acta Paediatr Scand. 1977 Sep;66(5):639-42. doi: 10.1111/j.1651-2227.1977.tb07961.x.

DOI:10.1111/j.1651-2227.1977.tb07961.x

Abstract

Neonatal thyrotoxicosis is a transient hyperthyroidism in infants of mothers with current or previous thyrotoxicosis. The pathogenesis have been accepted to be placental transfer of maternal thyroid stimulating immunoglobulins. Of two siblings from a previous thyrotoxic mother the first had marked symptoms of thyrotoxicosis but during the second pregnancy antithyroid treatment was given to the mother and though the child had high levels of thyroid hormones for 6 weeks it had only minimal symptoms of thyrotoxicosis.

摘要

新生儿甲状腺毒症是患有当前或既往甲状腺毒症的母亲所生婴儿中的一种短暂性甲状腺功能亢进症。其发病机制被认为是母体甲状腺刺激免疫球蛋白的胎盘转移。在一位既往患有甲状腺毒症的母亲所生的两个孩子中，第一个孩子有明显的甲状腺毒症症状，但在第二次怀孕期间，母亲接受了抗甲状腺治疗，尽管孩子的甲状腺激素水平在6周内一直很高，但仅有轻微的甲状腺毒症症状。