Kimbi H K, Fagbenro-Beyioku A F
Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Nigeria.
East Afr Med J. 1996 Oct;73(10):636-7.
The antimalarial activity of boiled water extracts of two medicinal plants (Cymbopogon giganteus and Enantia chlorantha) against chloroquine resistant Plasmodium yoelii nigeriensis in albino mice was assessed. Twenty-five mice were used for each extract. Each mouse was inoculated with approximately 10(5) erythrocytes infected with chloroquine-resistant P.y. nigeriensis. At five to seven percent parasitaemia, the mice were randomly divided into five groups of five mice each. The first four groups were treated intraperitoneally for three consecutive days with different doses of the stock solution per mouse. The two extracts cleared the infection in a dose-dependent manner.
评估了两种药用植物（巨香茅和绿花恩南蕃荔枝）的沸水提取物对白化病小鼠体内耐氯喹的约氏疟原虫尼日尔株的抗疟活性。每种提取物使用25只小鼠。每只小鼠接种约10(5)个感染耐氯喹约氏疟原虫尼日尔株的红细胞。在寄生虫血症达到5%至7%时，将小鼠随机分为五组，每组五只。前四组连续三天腹腔注射不同剂量的每只小鼠储备溶液。两种提取物均以剂量依赖方式清除感染。
