Bucci F A, Tanner J B, Moody K J, Myers P J
Center for Contact Lens Research, Pugliese Eye Specialists, Kingston, PA, USA.
CLAO J. 1997 Jan;23(1):43-8.
To compare the clinical performance of the Optima soft toric contact lens versus the CSI soft toric contact lens.
Twenty-one patients (five affected by allergies) were followed at 2-week intervals for 4 months in a prospective, randomized, double-masked study comparing the Optima soft toric contact lens to the CSI soft toric contact lens.
The patients preference evaluation revealed a statistically significant preference for the CIS toric lens in 14 of 16 variables including overall lens preference (P = 0.0001). The two remaining variables, lens awareness (P = 0.07) and foreign body sensation (P = 0.06), showed a trend toward a preference for the CSI toric lens. The less sensitive symptom ranking questionnaire revealed a significance for, or a trend toward, a significant difference in three of 10 variables, all in favor of the CSI toric lens. The mean degrees of axis rotation were 3.5* for the CSI lens and 7.6* for the Optima lens (P = 0.0001). Factor analysis identified a clustering of variables around specific ranked factors. Factors related to 1) allergy status (.93); 2) visual function (.87); 3) ocular surface (.82); and 4) refractive characteristics (.71) were most significant in determining the overall clinical performance of these toric lenses. Allergic patients significantly preferred the CSI toric lens for 15 of 16 variables, whereas non-allergic patients preferred the CSI lens for seven of 16 variables.
The patient preference, symptom ranking, and axis rotation analysis of this study revealed a superior performance by the CSI toric contact lens when compared to the Optima toric contact lens. Allergic patients revealed an even stronger and statistically significant preference for the CSI lens when compared to non-allergic patients.
比较Optima软性散光隐形眼镜与CSI软性散光隐形眼镜的临床性能。
在一项前瞻性、随机、双盲研究中，对21例患者（5例有过敏反应）每隔2周进行一次随访，为期4个月，比较Optima软性散光隐形眼镜与CSI软性散光隐形眼镜。
患者偏好评估显示，在16项变量中的14项，包括总体镜片偏好方面，对CSI散光镜片存在统计学上的显著偏好（P = 0.0001）。其余两项变量，即镜片感知度（P = 0.07）和异物感（P = 0.06），显示出对CSI散光镜片有偏好的趋势。较不敏感症状排名问卷显示，在10项变量中的3项存在显著差异或有显著差异的趋势，所有这些都有利于CSI散光镜片。CSI镜片的平均轴旋转度数为3.5°，Optima镜片为7.6°（P = 0.0001）。因子分析确定了围绕特定排名因素的变量聚类。与1）过敏状态（.93）；2）视觉功能（.87）；3）眼表（.82）；和4）屈光特征（.71）相关的因素在确定这些散光镜片的总体临床性能方面最为显著。过敏患者在16项变量中的15项显著偏好CSI散光镜片，而非过敏患者在16项变量中的7项偏好CSI镜片。
本研究的患者偏好、症状排名和轴旋转分析显示，与Optima散光隐形眼镜相比，CSI散光隐形眼镜性能更优。与非过敏患者相比，过敏患者对CSI镜片表现出更强且具有统计学意义的偏好。
