Sullivan J, Stanfield C N, Dackis C
Am J Psychiatry. 1977 Oct;134(10):1098-1103. doi: 10.1176/ajp.134.10.1098.
Previous reports have indicated that platelet MAO activity is low in some schizophrenic and other psychiatric patients. However, other studies have not been able to replicate this phenomenon. This study supportsthe previous observations of low enzyme activity in some chronic schizophrenic patients. The authors discuss the thesis that low platelet MAO activity may be a biochemical marker for vulnerability to psychiatric illness.
先前的报告表明,一些精神分裂症患者和其他精神病患者的血小板单胺氧化酶(MAO)活性较低。然而,其他研究未能重现这一现象。本研究支持了先前关于一些慢性精神分裂症患者酶活性较低的观察结果。作者讨论了血小板MAO活性较低可能是易患精神疾病的生化标志物这一论点。