Syntheses and pharmacological properties of new 2-aminobenzimidazole derivatives.

The paper reports the structures, syntheses and pharmacological properties of new compounds having a 2-aminobenzimidazole group. They exhibit various activities: histamine H1- and H2-receptors blocking activities, antilipidemic and platelet antiaggregatory, anti-inflammatory and analgesic properties, antimicrobial, fungicidal, parasiticide, antiarrythmic activity and muscle relaxant, comparable to those of drugs used in therapy.