针对丙型肝炎病毒核心蛋白和非结构3蛋白的抗体产生对T细胞功能缺陷高度敏感。
Antibody production against hepatitis C virus core and nonstructural 3 proteins is highly sensitive to deficits in T-cell function.
作者信息
Ando Y, Sönnerborg A, Barkholt L, Birkett A, Ericzon B G, Sällberg M
机构信息
Division of Clinical Virology, Huddinge University Hospital, Karolinska Institute, Sweden.
出版信息
Clin Diagn Lab Immunol. 1997 Jan;4(1):104-6. doi: 10.1128/cdli.4.1.104-106.1997.
Abstract
The influence of suppression of CD4+ and CD8+ T cells on the humoral responses to hepatitis C virus (HCV) core and nonstructural 3 proteins was studied. An increasing viral burden cannot substitute for the lack of functional T cells in maintaining humoral HCV-specific responses.
摘要
研究了CD4+和CD8+ T细胞抑制对丙型肝炎病毒（HCV）核心蛋白和非结构3蛋白体液免疫反应的影响。在维持体液性HCV特异性反应方面，不断增加的病毒载量无法替代功能性T细胞的缺乏。
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