Abramson D, Mills J T, Marquardt R R, Frohlich A A
Cereal Research Center, Agriculture and Agri-Food Canada, Winnipeg.
Can J Vet Res. 1997 Jan;61(1):49-52.
Feed samples from 94 cases involving fungal contamination and suspected mycotoxicosis of farm animals in western Canada were examined during 1982-1994 to assess the incidence of mycotoxins. Samples were analyzed for aflatoxins, ochratoxin A, citrinin, sterigmatocystin, and the fungal estrogen zearalenone. Samples infected with Fusarium fungi were additionally assayed for nivalenol, deoxynivalenol, fusarenone-x, 15-acetyl-deoxynivalenol, diacetoxyscirpenol, HT-2 toxin, and T-2 toxin. Mycotoxins were found in 21 feed samples from 17 cases (18% of the reported cases), generally at levels far below those needed to induce symptoms under laboratory conditions. HT-2 toxin and other type-A trichothecenes were detected in 5 samples, deoxynivalenol and other type-B trichothecenes in 13, ochratoxin A in 5, and citrinin in 2. In 9 cases, symptoms observed in the animals were consistent with the known effects of the mycotoxin(s) found in the particular feed samples.
1982年至1994年期间,对加拿大西部94例涉及家畜真菌污染和疑似霉菌毒素中毒的饲料样本进行了检测,以评估霉菌毒素的发生率。对样本进行了黄曲霉毒素、赭曲霉毒素A、桔霉素、杂色曲霉素和真菌雌激素玉米赤霉烯酮的分析。对感染镰刀菌的样本还检测了雪腐镰刀菌烯醇、脱氧雪腐镰刀菌烯醇、镰刀菌烯酮-X、15-乙酰脱氧雪腐镰刀菌烯醇、二醋酸藨草镰刀菌烯醇、HT-2毒素和T-2毒素。在17例病例的21个饲料样本中发现了霉菌毒素(占报告病例的18%),一般含量远低于在实验室条件下诱发症状所需的水平。在5个样本中检测到HT-2毒素和其他A型单端孢霉烯族毒素,13个样本中检测到脱氧雪腐镰刀菌烯醇和其他B型单端孢霉烯族毒素,5个样本中检测到赭曲霉毒素A,2个样本中检测到桔霉素。在9例病例中,动物观察到的症状与在特定饲料样本中发现的霉菌毒素的已知作用一致。