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加拿大西部屠宰猪血液中的赭曲霉毒素A。

Ochratoxin A in blood from slaughter pigs in western Canada.

作者信息

Marquardt R R, Frohlich A A, Sreemannarayana O, Abramson D, Bernatsky A

机构信息

University of Manitoba, Department of Animal Science, Winnipeg.

出版信息

Can J Vet Res. 1988 Apr;52(2):186-90.

Abstract

Twelve hundred blood samples were obtained in 1986 from pigs slaughtered in western Canada. The samples were assayed for ochratoxin as it is a potential contaminant in the food system. Blood ochratoxin concentration is a good indicator of tissue concentrations, particularly those in the liver and kidney. High performance liquid chromatography analysis of serum for ochratoxin demonstrated that 3.6 and 4.2% of the blood samples collected in February and March (n = 194) and May, June and July (n = 1006), respectively, had ochratoxin concentrations that exceeded 20 ng/mL. Overall the percent of samples that had concentrations of greater than 10, 20, 50, 100 and 200 ng/mL serum were 11.3, 4.1, 1.25, 0.42 and 0.08%, respectively. Samples that had ochratoxin concentrations that were greater than 20 ng/mL of serum were confirmed using two independent methods: liquid chromatography-mass spectrometry analysis and methyl ester derivatization followed by high performance liquid chromatography analysis.

摘要

1986年从加拿大西部屠宰的猪身上采集了1200份血样。对这些样本进行了赭曲霉毒素检测,因为它是食品系统中的一种潜在污染物。血液中赭曲霉毒素浓度是组织浓度的良好指标,尤其是肝脏和肾脏中的浓度。通过高效液相色谱法对血清中的赭曲霉毒素进行分析表明,分别在2月和3月(n = 194)以及5月、6月和7月(n = 1006)采集的血样中,有3.6%和4.2%的赭曲霉毒素浓度超过20 ng/mL。总体而言,血清浓度大于10、20、50、100和200 ng/mL的样本百分比分别为11.3%、4.1%、1.25%、0.42%和0.08%。血清中赭曲霉毒素浓度大于20 ng/mL的样本通过两种独立方法进行了确认:液相色谱 - 质谱分析以及甲酯衍生化后再进行高效液相色谱分析。

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Heat stability of ochratoxin A in pig products.
J Sci Food Agric. 1980 Dec;31(12):1313-5. doi: 10.1002/jsfa.2740311215.
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Screening for ochratoxin A in blood by flow injection analysis.
J Appl Toxicol. 1984 Dec;4(6):326-9. doi: 10.1002/jat.2550040609.
10
Studies on ochratoxins.赭曲霉毒素研究
CRC Crit Rev Toxicol. 1974 Jan;2(4):499-524. doi: 10.3109/10408447309025706.

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