氧化孢菌素：一种来自尖孢镰刀菌的新型抗真菌N-甲基-4-羟基-2-吡啶酮。
Oxysporidinone: a novel, antifungal N-methyl-4-hydroxy-2-pyridone from Fusarium oxysporum.
作者信息
Breinhold J, Ludvigsen S, Rassing B R, Rosendahl C N, Nielsen S E, Olsen C E
机构信息
Novo Nordisk A/S, Bagsvaerd, Denmark.
出版信息
J Nat Prod. 1997 Jan;60(1):33-5. doi: 10.1021/np9605596.
PMID:9014349
Abstract
Oxysporidinone (1), a novel 3,5-disubstituted N-methyl-4-hydroxy-2-pyridone, was isolated from fermentations of Fusarium oxysporum (CBS 330.95) by counter-current chromatography. The structure was determined by spectroscopic methods including NMR, MS, IR, and UV analysis. Oxysporidinone exhibited growth inhibitory activity against several common plant pathogenic fungi.
摘要
氧孢菌素酮（1）是一种新型的3,5-二取代N-甲基-4-羟基-2-吡啶酮，通过逆流色谱法从尖孢镰刀菌（CBS 330.95）的发酵产物中分离得到。其结构通过包括核磁共振（NMR）、质谱（MS）、红外光谱（IR）和紫外分析（UV）在内的光谱方法确定。氧孢菌素酮对几种常见的植物病原真菌表现出生长抑制活性。
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