Thomas R H, Ridley C M, McGibbon D H, Black M M
Salisbury District Hospital, Wiltshire, England.
J R Soc Med. 1996 Dec;89(12):694-8. doi: 10.1177/014107689608901210.
A study of 350 women with lichen sclerosus, originally made to elucidate the relationship between lichen sclerosus and autoimmunity, led to the amassing of a considerable amount of clinical material. Our review is confined to those with anogenital lesions (342), supplemented by some new cases (15), giving a total of 357 women with biopsy proven lichen sclerosus. It demonstrates the wide age range of the condition, the association with morphoea and lichen planus and the occurrence of squamous cell carcinoma in some cases. It also shows that inappropriate surgery has continued to be carried out for benign disease.
一项针对350例硬化性苔藓女性患者的研究，最初旨在阐明硬化性苔藓与自身免疫之间的关系，积累了大量临床资料。我们的综述限于有肛门生殖器病变的患者（342例），并补充了一些新病例（15例），共有357例经活检证实为硬化性苔藓的女性。它表明了该病的年龄范围广泛，与硬斑病和扁平苔藓有关，以及在某些病例中发生鳞状细胞癌。它还表明，针对良性疾病仍在进行不适当的手术。
