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女性肛门生殖器硬化性苔藓

Anogenital lichen sclerosus in women.

作者信息

Thomas R H, Ridley C M, McGibbon D H, Black M M

机构信息

Salisbury District Hospital, Wiltshire, England.

出版信息

J R Soc Med. 1996 Dec;89(12):694-8. doi: 10.1177/014107689608901210.

Abstract

A study of 350 women with lichen sclerosus, originally made to elucidate the relationship between lichen sclerosus and autoimmunity, led to the amassing of a considerable amount of clinical material. Our review is confined to those with anogenital lesions (342), supplemented by some new cases (15), giving a total of 357 women with biopsy proven lichen sclerosus. It demonstrates the wide age range of the condition, the association with morphoea and lichen planus and the occurrence of squamous cell carcinoma in some cases. It also shows that inappropriate surgery has continued to be carried out for benign disease.

摘要

一项针对350例硬化性苔藓女性患者的研究,最初旨在阐明硬化性苔藓与自身免疫之间的关系,积累了大量临床资料。我们的综述限于有肛门生殖器病变的患者(342例),并补充了一些新病例(15例),共有357例经活检证实为硬化性苔藓的女性。它表明了该病的年龄范围广泛,与硬斑病和扁平苔藓有关,以及在某些病例中发生鳞状细胞癌。它还表明,针对良性疾病仍在进行不适当的手术。

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本文引用的文献

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Bilateral vulvar basal cell carcinomata.双侧外阴基底细胞癌
J Am Acad Dermatol. 1993 May;28(5 Pt 2):836-8. doi: 10.1016/0190-9622(93)70112-7.
3
Mucosal lichen sclerosus/lichen planus overlap syndromes.黏膜硬化性苔藓/扁平苔藓重叠综合征
Br J Dermatol. 1994 Jul;131(1):118-23. doi: 10.1111/j.1365-2133.1994.tb08468.x.
4
The aetiology of vulval neoplasia.外阴肿瘤的病因学。
Br J Obstet Gynaecol. 1994 Aug;101(8):655-7. doi: 10.1111/j.1471-0528.1994.tb13178.x.
6
Lichen sclerosus.硬化性苔藓
J Am Acad Dermatol. 1995 Mar;32(3):393-416; quiz 417-8. doi: 10.1016/0190-9622(95)90060-8.
10
Lichen sclerosus et atrophicus.硬化萎缩性苔藓
Trans St Johns Hosp Dermatol Soc. 1971;57(1):9-30.

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