Mewes H W, Albermann K, Heumann K, Liebl S, Pfeiffer F
MIPS, Max-Planck-Institut für Biochemie, Am Klopferspitz 18, D-82152 Martinsried, Germany.
Nucleic Acids Res. 1997 Jan 1;25(1):28-30. doi: 10.1093/nar/25.1.28.
The MIPS group (Martinsried Institute for Protein Sequences) at the Max-Planck-Institute for Biochemistry, Martinsried near Munich, Germany, collects, processes and distributes protein sequence data within the framework of the tripartite association of the PIR-International Protein Sequence Database (,). MIPS contributes nearly 50% of the data input to the PIR-International Protein Sequence Database. The database is distributed on CD-ROM together with PATCHX, an exhaustive supplement of unique, unverified protein sequences from external sources compiled by MIPS. Through its WWW server (http://www.mips.biochem.mpg.de/ ) MIPS permits internet access to sequence databases, homology data and to yeast genome information. (i) Sequence similarity results from the FASTA program () are stored in the FASTA database for all proteins from PIR-International and PATCHX. The database is dynamically maintained and permits instant access to FASTA results. (ii) Starting with FASTA database queries, proteins have been classified into families and superfamilies (PROT-FAM). (iii) The HPT (hashed position tree) data structure () developed at MIPS is a new approach for rapid sequence and pattern searching. (iv) MIPS provides access to the sequence and annotation of the complete yeast genome (), the functional classification of yeast genes (FunCat) and its graphical display, the 'Genome Browser' (). A CD-ROM based on the JAVA programming language providing dynamic interactive access to the yeast genome and the related protein sequences has been compiled and is available on request.
位于德国慕尼黑附近马丁斯里德的马克斯 - 普朗克生物化学研究所的MIPS小组（马丁斯里德蛋白质序列研究所），在PIR - 国际蛋白质序列数据库三方合作的框架内收集、处理和分发蛋白质序列数据。MIPS为PIR - 国际蛋白质序列数据库贡献了近50%的数据输入。该数据库与PATCHX一起以光盘形式发行，PATCHX是MIPS汇编的来自外部来源的独特、未经证实的蛋白质序列的详尽补充。通过其万维网服务器（http://www.mips.biochem.mpg.de/ ），MIPS允许通过互联网访问序列数据库、同源性数据和酵母基因组信息。（i）来自FASTA程序（）的序列相似性结果存储在FASTA数据库中，涵盖PIR - 国际和PATCHX的所有蛋白质。该数据库动态维护，可即时访问FASTA结果。（ii）从FASTA数据库查询开始，蛋白质已被分类为家族和超家族（PROT - FAM）。（iii）MIPS开发的HPT（哈希位置树）数据结构（）是一种用于快速序列和模式搜索新方法。（iv）MIPS提供对完整酵母基因组的序列和注释（）、酵母基因的功能分类（FunCat）及其图形显示“基因组浏览器”（）的访问。基于JAVA编程语言的光盘已编制完成，可提供对酵母基因组及相关蛋白质序列的动态交互式访问，可应要求提供。
