The promotion of V region hypermutation.
作者信息
Scharff M D, Poltoratsky V, Green N S
机构信息
Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
出版信息
J Exp Med. 1997 Jan 20;185(2):185-8. doi: 10.1084/jem.185.2.185.
Abstract
摘要
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本文引用的文献
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J Exp Med. 1997 Jan 20;185(2):239-50. doi: 10.1084/jem.185.2.239.
2
Relationships between DNA repair and transcription.DNA修复与转录之间的关系。
Annu Rev Biochem. 1996;65:15-42. doi: 10.1146/annurev.bi.65.070196.000311.
3
Rearrangement/hypermutation/gene conversion: when, where and why?重排/超突变/基因转换：何时、何地以及为何发生？
Immunol Today. 1996 Feb;17(2):92-7. doi: 10.1016/0167-5699(96)80586-x.
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Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells.正常和自身反应性B细胞中体细胞突变的二核苷酸和三核苷酸靶点偏好性。
J Immunol. 1996 Apr 1;156(7):2642-52.
5
The targeting of somatic hypermutation.体细胞高频突变的靶向作用。
Semin Immunol. 1996 Jun;8(3):159-68. doi: 10.1006/smim.1996.0020.
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Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches.利用传统转基因和转基因同源重组方法对小鼠抗体V基因体细胞超突变所需的顺式作用元件进行表征。
Semin Immunol. 1996 Jun;8(3):141-50. doi: 10.1006/smim.1996.0018.
7
The mechanism of somatic hypermutation studied with transgenic and transfected target genes.利用转基因和转染的靶基因研究体细胞超突变的机制。
Semin Immunol. 1996 Jun;8(3):131-40. doi: 10.1006/smim.1996.0017.
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The molecular basis of somatic hypermutation of immunoglobulin genes.免疫球蛋白基因体细胞超突变的分子基础。
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Normal human IgD+IgM- germinal center B cells can express up to 80 mutations in the variable region of their IgD transcripts.正常人类IgD+IgM-生发中心B细胞在其IgD转录本的可变区可表达多达80个突变。
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