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正常人类前列腺及良性前列腺增生的光学显微镜体视学分析

Light microscopic stereological analysis of the normal human prostate and of benign prostatic hyperplasia.

作者信息

Bartsch G, Müller H R, Oberholzer M, Rohr H P

出版信息

J Urol. 1979 Oct;122(4):487-91. doi: 10.1016/s0022-5347(17)56476-9.

DOI:10.1016/s0022-5347(17)56476-9
PMID:90177
Abstract

Normal prostate glands from 6 men less than 30 years old and enucleated tissue of benign prostatic hyperplasia were analyzed by stereological methods. Studies on the relative volumetric amount of fibromuscular (stromal) and glandular areas of the gland reveal no statistically significant difference between the inner and outer parts of the normal prostate and between the inner part of the normal prostate and benign prostatic hyperplasia. However, in benign prostatic hyperplasia there is a significant increase in the volumetric amount of the fibromuscular tissue and a decrease in the glandular area compared to the outer part of the normal prostate and the whole normal prostate (sum of the inner and the outer parts). These stereological data are discussed with respect to the pathogenesis of benign prostatic hyperplasia.

摘要

采用体视学方法分析了6名年龄小于30岁男性的正常前列腺以及前列腺良性增生的摘除组织。对前列腺纤维肌肉(基质)和腺区相对体积量的研究表明,正常前列腺的内部和外部之间、正常前列腺内部与前列腺良性增生之间在统计学上无显著差异。然而,与正常前列腺外部及整个正常前列腺(内部和外部之和)相比,前列腺良性增生时纤维肌肉组织的体积量显著增加,腺区减少。结合前列腺良性增生的发病机制对这些体视学数据进行了讨论。

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