Kanda H, Nimura Y, Yasui A, Nakano S, Kumada S, Shionoya S
First Department of Surgery, Nagoya University School of Medicine, Showa-ku, Japan.
Surg Today. 1997;27(2):120-3. doi: 10.1007/BF02385899.
Using an ultrasonic Doppler system, we prospectively studied the changes in portal venous flow (PVF) following percutaneous transhepatic biliary drainage (PTBD) and evaluated the correlation between PVF and liver function in 10 patients with obstructive jaundice. The patients were divided into two groups according to their rate of decrease in serum bilirubin ("b"). Group A comprised 5 patients with a "b" of less than -0.1, while group B consisted of 5 patients who did not meet this criterion. The mean PVF increased following PTBD (P < 0.01). The increase in PVF was due to an increase in the maximum velocity of the portal vein (Vmax). The rate of increase in the Vmax in group A was significantly higher than that in group B on both the 7th and 14th postdrainage days (P < 0.05). The rate of increase in the Vmax correlated significantly with the rate of decrease in the serum bilirubin concentration (P < 0.01). Based on the above findings, we conclude that measuring the Vmax by Doppler ultrasonography is useful in evaluating the liver function in patients with obstructive jaundice.
我们使用超声多普勒系统,对10例梗阻性黄疸患者经皮经肝胆道引流(PTBD)后门静脉血流(PVF)的变化进行了前瞻性研究,并评估了PVF与肝功能之间的相关性。根据血清胆红素(“b”)下降速率将患者分为两组。A组包括5例“b”小于-0.1的患者,而B组由5例不符合该标准的患者组成。PTBD后平均PVF增加(P<0.01)。PVF的增加是由于门静脉最大流速(Vmax)增加所致。在引流后第7天和第14天,A组Vmax的增加速率均显著高于B组(P<0.05)。Vmax的增加速率与血清胆红素浓度的下降速率显著相关(P<0.01)。基于上述发现,我们得出结论,通过多普勒超声测量Vmax有助于评估梗阻性黄疸患者的肝功能。