Plotnikov M B, Smol'iakova V I, Chernysheva G A, Ivanova E V, Zverev Ia F
Eksp Klin Farmakol. 1996 Sep-Oct;59(5):29-30.
The mechanism of the diuretic effect of the new drug polyosm, polyethylene oxide 400 solution, was studied in experiments on anesthetized cats. Intravenous polyosm infusion was attended with a marked diuretic and natriuretic effect developing due to reduced reabsorption of water and natrium and increased glomerular filtration.
