Landyshev S Iu
Probl Tuberk. 1996(4):41-3.
A quantitative technique was used to microbiological study of sputum in 110 patients with acute pneumonia and 56 with advanced pneumonia, in 38 of them, their bronchoalveolar lavage fluid was simultaneously examined. In acute pneumonia, Pneumococcus was most commonly (71.8%) cultured, frequently in combination with other microorganisms, mainly with Neisseria and Enterobacteriaceae. These patients were found to have higher pneumococcal cultivation rates (83.0%) in the bronchoalveolar lavage fluid. Following 3 weeks of etiotropic therapy, the pneumococcal cultivation rates dropped to 10.8%. Pneumococcus also occupied the leading place (69.6%) in the etiology of advanced pneumonia, Mycoplasma pneumoniae was detected by the indirect immunofluorescence test in 28.5% of patients. After 3-week therapy, the cultivation rates for Pneumococcus decreased to 23.0%, its association with other microbes being more frequently observed. At the same time there was a rise in the detection rate of Mycoplasma antigen, which could cause advanced pneumonia.
采用定量技术对110例急性肺炎患者和56例晚期肺炎患者的痰液进行微生物学研究，其中38例同时检测了支气管肺泡灌洗液。在急性肺炎中，肺炎球菌培养最为常见（71.8%），常与其他微生物合并存在，主要是奈瑟菌属和肠杆菌科。这些患者支气管肺泡灌洗液中的肺炎球菌培养率更高（83.0%）。经过3周的病因特异性治疗后，肺炎球菌培养率降至10.8%。肺炎球菌在晚期肺炎病因中也占主导地位（69.6%），28.5%的患者通过间接免疫荧光试验检测到肺炎支原体。经过3周治疗后，肺炎球菌的培养率降至23.0%，其与其他微生物的合并存在更为常见。与此同时，可导致晚期肺炎的支原体抗原检测率有所上升。
