Nishigami T, Yamada M, Nakasho K, Yamamura M, Satomi M, Uematsu K, Ri G, Mizuta T, Fukumoto H
Department of Pathology, Hyogo College of Medicine, Nishinomiya.
Intern Med. 1996 Dec;35(12):953-6. doi: 10.2169/internalmedicine.35.953.
A classical carcinoid tumor, measuring 11 x 17 mm, was found in a 41-year-old woman in the neck of the gall bladder. The lesion infiltrated the muscular layer of the gall bladder wall. Histologically, the tumor was positive for only Grimelius and chromogranin A stains. In a literature search, approximately half of the tumors reported as gall bladder carcinoid tumor appear to be actually endocrine cell carcinomas, which are completely different from classical carcinoid tumors with respect to size, metastasis and prognosis. These carcinomas should not be termed as carcinoid tumors from both the clinical and histological points of view, and should be clearly distinguished from benign lesions when reported.
在一名41岁女性的胆囊颈部发现了一个大小为11×17毫米的经典类癌肿瘤。该病变浸润了胆囊壁的肌层。组织学上，该肿瘤仅对 Grimelius 和嗜铬粒蛋白A染色呈阳性。在文献检索中，报告为胆囊类癌肿瘤的肿瘤中约有一半似乎实际上是内分泌细胞癌，它们在大小、转移和预后方面与经典类癌肿瘤完全不同。从临床和组织学角度来看，这些癌不应被称为类癌肿瘤，报告时应与良性病变明确区分。
