Delfino R J, Murphy-Moulton A M, Burnett R T, Brook J R, Becklake M R
Department of Medicine, University of California, Irvine, USA.
Am J Respir Crit Care Med. 1997 Feb;155(2):568-76. doi: 10.1164/ajrccm.155.2.9032196.
As an approach to evaluating the public health burden from current air pollution levels, we examined the relationship of daily emergency room (ER) visits for respiratory illnesses (25 hospitals, average 98 visits/d) to air pollution in Montreal, Canada, from June through September, 1992 and 1993. Air pollutants measured included ozone (O3), particulate matter diameter < 10 microm (PM10) and < 2.5 microm (PM2.5), the sulfate fraction of PM2.5 (SO4), and aerosol strong acidity (H+). Temporal trends, autocorrelation, and weather were controlled for in time-series regressions. For 1992, no significant associations with ER visits were found. However, 33% of the particulate data were missing. For 1993, 1-h maximum O3, PM10, PM2.5, and SO4 were all positively associated with respiratory visits for patients over 64 yr of age (p < 0.02). An increase to the mean level of 1-h maximum O3 (36 ppb) was associated with a 21% increase over the mean number of daily ER visits (95% confidence interval [CI]: 8 to 34%). Effects of particulates were smaller, with mean increases of 16% (4 to 28%), 12% (2 to 21%) and 6% (1 to 12%) for PM10, PM2.5, and SO4, respectively. Relative mass effects were PM2.5 > PM10 >> SO4. Ozone and PM10 levels never exceeded 67 ppb and 51 microg/m3, respectively (well below the U.S. National Ambient Air Quality Standards of 120 ppb and 150 microg/m3, respectively). The present findings have public health implications with regard to the adverse health effects of urban photochemical air pollution on older individuals.
作为评估当前空气污染水平对公众健康负担的一种方法,我们研究了1992年6月至9月以及1993年期间,加拿大蒙特利尔25家医院(平均每日98次就诊)因呼吸系统疾病而进行的每日急诊室(ER)就诊次数与空气污染之间的关系。所测量的空气污染物包括臭氧(O3)、直径小于10微米(PM10)和小于2.5微米(PM2.5)的颗粒物、PM2.5的硫酸盐部分(SO4)和气溶胶强酸度(H+)。在时间序列回归中对时间趋势、自相关和天气进行了控制。1992年,未发现与急诊室就诊有显著关联。然而,33%的颗粒物数据缺失。1993年,64岁以上患者的1小时最大O3、PM10、PM2.5和SO4均与呼吸道就诊呈正相关(p < 0.02)。1小时最大O3平均水平增加到36 ppb与每日急诊室就诊平均次数增加21%相关(95%置信区间[CI]:8%至34%)。颗粒物的影响较小,PM10、PM2.5和SO4的平均增加分别为16%(4%至28%)、12%(2%至21%)和6%(1%至12%)。相对质量效应为PM2.5 > PM10 >> SO4。臭氧和PM10水平分别从未超过67 ppb和51微克/立方米(远低于美国国家环境空气质量标准的120 ppb和150微克/立方米)。目前的研究结果对于城市光化学空气污染对老年人的不良健康影响具有公共卫生意义。