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蒙特利尔老年人因呼吸道疾病前往急诊室就诊情况:与低水平臭氧暴露的关联

Emergency room visits for respiratory illnesses among the elderly in Montreal: association with low level ozone exposure.

作者信息

Delfino R J, Murphy-Moulton A M, Becklake M R

机构信息

Department of Medicine, University of California at Irvine 92717, USA.

出版信息

Environ Res. 1998 Feb;76(2):67-77. doi: 10.1006/enrs.1997.3794.

Abstract

Population-based studies of hospital usage have been used to identify the ongoing adverse impacts of photochemical air pollutants on respiratory health. In this study we examined the relationship between the number of daily emergency room (ER) visits for respiratory illnesses (25 hospitals) and outdoor air pollution in Montreal, Quebec (June-August, 1989-1990). Air pollutants measured included 1- and 8-h maximum ozone (O3) and estimated particulate matter < 2.5 microns in aerometric diameter (PM2.5). Seasonal and day-of-week trends, autocorrelation, temperature, and relative humidity were controlled for in-time series regressions. Although O3 levels never exceeded the U.S. National Ambient Air Quality Standard (NAAQS) of 120 ppb (maximum day, 106 ppb), statistically significant (P < 0.01) relationships were found between respiratory ER visits for patients over the age of 64 and both 1- and 8-h maximum O3 measured 1 day prior to the ER visit day during the 1989 summer: ER visits were 18.7% higher than average (95% Cl, 6.5-30.9%) for a mean increase of 44 ppb O3 (1-h maximum), and 21.8% higher than average (95% Cl, 9.7-33.8%) for a mean increase of 38 ppb O3 (8-h maximum). There was an association between respiratory ER visits for the elderly and estimated PM2.5 lagged 1 day (0.1 visit/microgram/m3 PM2.5, P < 0.07), but this was confounded by both temperature and O3. The only finding for a reference group of nonrespiratory conditions was an inverse association between ER visits for infants and O3, but this was confounded by weather. These findings confirm the impression that while air quality standards may protect the respiratory health of the general population, this is not the case for susceptible subgroups such as the elderly.

摘要

基于人群的医院使用情况研究已被用于确定光化学空气污染物对呼吸健康的持续不利影响。在本研究中,我们调查了魁北克省蒙特利尔市(1989年6月至1990年8月)25家医院因呼吸系统疾病的每日急诊室就诊次数与室外空气污染之间的关系。测量的空气污染物包括1小时和8小时最大臭氧(O3)以及空气动力学直径小于2.5微米的估计颗粒物(PM2.5)。在时间序列回归中控制了季节和星期几的趋势、自相关、温度和相对湿度。尽管O3水平从未超过美国国家环境空气质量标准(NAAQS)的120 ppb(最大日,106 ppb),但在1989年夏季,64岁以上患者的呼吸系统急诊室就诊次数与急诊就诊日前一天测量的1小时和8小时最大O3之间发现了具有统计学意义(P < 0.01)的关系:对于O3平均增加44 ppb(1小时最大值),急诊就诊次数比平均水平高18.7%(95% Cl,6.5 - 30.9%),对于O3平均增加38 ppb(8小时最大值),急诊就诊次数比平均水平高21.8%(95% Cl,9.7 - 33.8%)。老年人呼吸系统急诊室就诊次数与滞后1天的估计PM2.5之间存在关联(0.1次就诊/微克/立方米PM2.5,P < 0.07),但这受到温度和O3两者的混杂影响。非呼吸系统疾病参考组的唯一发现是婴儿急诊室就诊次数与O3之间存在负相关,但这受到天气的混杂影响。这些发现证实了这样一种印象,即虽然空气质量标准可能保护一般人群的呼吸健康,但对于老年人等易感亚组并非如此。

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