César L A, Ramires J A, Serrano Júnior C V, Meneghetti J C, Antonelli R H, da-Luz P L, Pileggi F J
Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, Brasil.
Braz J Med Biol Res. 1996 May;29(5):605-13.
To determine whether or not slow coronary flow (SF) depends on hemodynamic variables, we studied 17 patients (15 men, mean age = 47.8 years) with SF at coronariography. Exercise thallium-201 myocardial scintigraphy revealed perfusion abnormalities in 13 (76.4%) patients. We then selected 89 individuals submitted to cinecoronariography for comparison: 15 were normal and 74 had heart disease. The coronary flow velocity was evaluated by the number of heart beats (HB) needed for coronary artery dye filling. The patients in the SF group had normal hemodynamic variables which were significantly different from those of patients with heart disease (P = 0.001). Patients with heart disease needed no more than 4 HB to fill their arteries, in contrast to 6.88 +/- 1.68 (5 to 11) in the SF group (P < 0.0001). Thus, in our patients with myocardial scintigraphy suggesting ischemia, SF was found to be an event which did not depend on hemodynamic factors.
为了确定冠状动脉血流缓慢（SF）是否取决于血流动力学变量，我们对17例冠状动脉造影显示有SF的患者（15例男性，平均年龄 = 47.8岁）进行了研究。运动铊-201心肌闪烁显像显示13例（76.4%）患者有灌注异常。然后我们选择89例接受冠状动脉电影造影的个体进行比较：15例正常，74例有心脏病。通过冠状动脉染料充盈所需的心跳次数（HB）评估冠状动脉血流速度。SF组患者的血流动力学变量正常，与心脏病患者的血流动力学变量有显著差异（P = 0.001）。心脏病患者动脉充盈所需的HB不超过4次，而SF组为6.88±1.68（5至11次）（P < 0.0001）。因此，在我们的心肌闪烁显像提示有缺血的患者中，发现SF是一种不依赖于血流动力学因素的情况。
