Gray F
Laboratoire de Neuropathologie, Hôpital Raymond Poincaré-Faculté de Médecine Paris-Quest, Garches, France.
Brain Pathol. 1997 Jan;7(1):629-47. doi: 10.1111/j.1750-3639.1997.tb01079.x.
The organisms that produce bacterial infections of the nervous system in tropical regions are similar to those existing in the rest of the world. However, because of poor socio-economic conditions in the former areas, preventing the implementation of appropriate prophylactic and therapeutic measures, the incidence and course of these diseases may vary. In this paper the neuropathological appearances of the main bacterial diseases are reviewed and the main differences between those occurring in developed and developing countries emphasized. Despite great efforts by governments and communities, tuberculosis still remains a scourge in many countries and leprosy has not been eradicated from earth. Earlier optimism that antibiotics could finally put an end to syphilis have been dashed and the disease still persists. Moreover, the explosion of AIDS not only has produced a recrudescence of many of these diseases, but has also changed their clinical and pathological presentation.
在热带地区引起神经系统细菌感染的病原体与世界其他地区存在的病原体相似。然而,由于前一类地区社会经济条件较差,阻碍了适当预防和治疗措施的实施,这些疾病的发病率和病程可能有所不同。本文回顾了主要细菌性疾病的神经病理学表现,并强调了发达国家和发展中国家所发生疾病之间的主要差异。尽管政府和社区付出了巨大努力,但结核病在许多国家仍然是一大祸害,麻风病也尚未从地球上根除。早期认为抗生素最终能终结梅毒的乐观情绪已破灭,该疾病仍然存在。此外,艾滋病的爆发不仅使其中许多疾病再度流行,还改变了它们的临床和病理表现。