Shiomi Y, Nagamine T, Fujiki N, Hirano S, Naito Y, Shibasaki H, Honjo I
Department of Hearing and Speech Science, Faculty of Medicine, Kyoto University, Japan.
Acta Otolaryngol. 1997 Jan;117(1):31-4. doi: 10.3109/00016489709117987.
An auditory-evoked magnetic field was recorded before and during tinnitus remission induced by an intravenous lidocaine injection. One and 4 kHz probe tones were presented monaurally in four tinnitus patients, and the responses were recorded using a 122-channel magnetometer. Three normal volunteers were also examined as controls. In tinnitus patients, the N100 m peak became sharper, while there was no marked change except for slight reduction in amplitude in normal subjects. Tinnitus remission by lidocaine may be related to attenuation of a masking-like effect of tinnitus on the sound-evoked responses.
在静脉注射利多卡因诱导耳鸣缓解之前和期间记录听觉诱发磁场。对4名耳鸣患者单耳呈现1kHz和4kHz的探测音,并使用122通道磁力计记录反应。还检查了3名正常志愿者作为对照。在耳鸣患者中,N100m波峰变得更尖锐,而在正常受试者中除了幅度略有降低外没有明显变化。利多卡因引起的耳鸣缓解可能与耳鸣对声音诱发反应的掩蔽样效应的减弱有关。