台湾地区乳腺癌病例对照研究——一个低发病率地区
A case-control study of breast cancer in Taiwan--a low-incidence area.
作者信息
Yang P S, Yang T L, Liu C L, Wu C W, Shen C Y
机构信息
Mackay Memorial Hospital, Academia Sinica, Taipei, Taiwan.
出版信息
Br J Cancer. 1997;75(5):752-6. doi: 10.1038/bjc.1997.133.
Abstract
To investigate risk factors for breast cancer in Taiwan, a low-incidence area, a case-control study was conducted. This comprised 244 subjects with diagnosed and pathologically confirmed breast cancer (age range 20-80 years) and 450 female ophthalmology outpatients as controls. Univariate and multiple logistic regression analysis suggests that breast cancer in Taiwan is aetiologically similar to breast cancer in high to moderate-incidence areas. A family history of breast cancer appears to be the most important factor contributing to the risk of breast cancer (odds ratio = 4.69). The effect of reproductive hormones (represented by the years of history of menses in premenopausal women, odds ratio = 3.35; or the age at menarche in post-menopausal women, odds ratio = 2.67) plays a significant role in tumorigenesis. Breast feeding appears to be a particularly important protective factor in Taiwanese women (odds ratio = 0.57).
摘要
为了调查低发病率地区台湾乳腺癌的风险因素，开展了一项病例对照研究。该研究包括244例经诊断和病理确诊的乳腺癌患者（年龄范围20 - 80岁）以及450名女性眼科门诊患者作为对照。单因素和多因素逻辑回归分析表明，台湾的乳腺癌在病因上与高至中等发病率地区的乳腺癌相似。乳腺癌家族史似乎是导致乳腺癌风险的最重要因素（优势比 = 4.69）。生殖激素的影响（以绝经前女性的月经史年限表示，优势比 = 3.35；或以绝经后女性的初潮年龄表示，优势比 = 2.67）在肿瘤发生中起重要作用。母乳喂养似乎是台湾女性特别重要的保护因素（优势比 = 0.57）。
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本文引用的文献
1
Identification of the breast cancer susceptibility gene BRCA2.乳腺癌易感基因BRCA2的鉴定。
Nature. 1995;378(6559):789-92. doi: 10.1038/378789a0.
2
Estimates of the worldwide incidence of eighteen major cancers in 1985.1985年全球18种主要癌症的发病率估计。
Int J Cancer. 1993 Jun 19;54(4):594-606. doi: 10.1002/ijc.2910540413.
3
Reproductive factors and breast cancer.生殖因素与乳腺癌
Epidemiol Rev. 1993;15(1):36-47. doi: 10.1093/oxfordjournals.epirev.a036115.
4
Breast cancer epidemiology: summary and future directions.乳腺癌流行病学：总结与未来方向
Epidemiol Rev. 1993;15(1):256-63. doi: 10.1093/oxfordjournals.epirev.a036112.
5
Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk.雌激素、孕激素、正常乳腺细胞增殖与乳腺癌风险。
Epidemiol Rev. 1993;15(1):17-35. doi: 10.1093/oxfordjournals.epirev.a036102.
6
Alcohol consumption and risk of breast cancer: a review of the epidemiologic evidence.饮酒与乳腺癌风险：流行病学证据综述
Epidemiol Rev. 1993;15(1):133-44. doi: 10.1093/oxfordjournals.epirev.a036097.
7
Diet, body size, and breast cancer.饮食、体型与乳腺癌。
Epidemiol Rev. 1993;15(1):110-32. doi: 10.1093/oxfordjournals.epirev.a036096.
8
Migration patterns and breast cancer risk in Asian-American women.亚裔美国女性的移民模式与乳腺癌风险
J Natl Cancer Inst. 1993 Nov 17;85(22):1819-27. doi: 10.1093/jnci/85.22.1819.
9
Cancer mortality among Chinese migrants: a review.
Int J Epidemiol. 1995 Apr;24(2):255-65. doi: 10.1093/ije/24.2.255.
10
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