在没有精神疾病的慢性疲劳综合征患者中，认知功能会受到损害。
Cognitive functioning is impaired in patients with chronic fatigue syndrome devoid of psychiatric disease.
作者信息
DeLuca J, Johnson S K, Ellis S P, Natelson B H
机构信息
University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, USA.
出版信息
J Neurol Neurosurg Psychiatry. 1997 Feb;62(2):151-5. doi: 10.1136/jnnp.62.2.151.
Abstract
OBJECTIVE
To examine the effect of the presence or absence of psychiatric disease on cognitive functioning in chronic fatigue syndrome.
METHODS
Thirty six patients with chronic fatigue syndrome and 31 healthy controls who did not exercise regularly were studied. Subgroups within the chronic fatigue syndrome sample were formed based on the presence or absence of comorbid axis I psychiatric disorders. Patients with psychiatric disorders preceding the onset chronic fatigue syndrome were excluded. Subjects were administered a battery of standardised neuropsychological tests as well as a structured psychiatric interview.
RESULTS
Patients with chronic fatigue syndrome without psychiatric comorbidity were impaired relative to controls and patients with chronic fatigue syndrome with concurrent psychiatric disease on tests of memory, attention, and information processing.
CONCLUSION
Impaired cognition in chronic fatigue syndrome cannot be explained solely by the presence of a psychiatric condition.
摘要
目的
研究精神疾病的有无对慢性疲劳综合征认知功能的影响。
方法
对36例慢性疲劳综合征患者和31例不经常运动的健康对照者进行研究。根据是否合并Ⅰ轴精神障碍，在慢性疲劳综合征样本中形成亚组。排除在慢性疲劳综合征发病前患有精神疾病的患者。受试者接受了一系列标准化神经心理学测试以及结构化精神访谈。
结果
在记忆、注意力和信息处理测试中，无精神疾病合并症的慢性疲劳综合征患者相对于对照组和伴有精神疾病的慢性疲劳综合征患者存在损害。
结论
慢性疲劳综合征中的认知损害不能仅用精神疾病来解释。
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