Gebel T, Kevekordes S, Pav K, Edenharder R, Dunkelberg H
Medical Institute for General Hygiene and Environmental Health, Georg-August-Universität, Göttingen, Germany.
Arch Toxicol. 1997;71(3):193-7. doi: 10.1007/s002040050375.
The herbicides alachlor, atrazine, terbuthylazine, gluphosinate-ammonium, isoproturon, pendimethaline and trifluralin were tested for genotoxicity in the mouse bone-marrow micronucleus test (MNT). Both atrazine and trifluraline caused a significant increase in the number of micronuclei at doses of 1,400 mg/kg body weight in female mice only. Alachlor, terbuthylazine, gluphosinate-ammonium, isoproturon and pendimethaline did not have any genotoxic effect in the mouse bone-marrow micronucleus test in either female or male animals.
对除草剂甲草胺、莠去津、特丁津、草铵膦铵盐、异丙隆、二甲戊灵和氟乐灵进行了小鼠骨髓微核试验（MNT）的遗传毒性测试。仅在雌性小鼠中，莠去津和氟乐灵在剂量为1400毫克/千克体重时导致微核数量显著增加。甲草胺、特丁津、草铵膦铵盐、异丙隆和二甲戊灵在雌性或雄性动物的小鼠骨髓微核试验中均未产生任何遗传毒性作用。
