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[被动吸烟与肺癌:一份新报告的视角]

[Passive smoking and lung cancer: a new report in perspective].

作者信息

van Barneveld T A, Borst P, van Leeuwen F E

机构信息

Het Nederlands Kanker Instituut, Amsterdam, Afd. Epidemiologie.

出版信息

Ned Tijdschr Geneeskd. 1997 Jan 18;141(3):132-6.

PMID:9053758
Abstract

Recently, a working group of six European scientists published a report on exposure to environmental tobacco smoke and the risk of lung cancer. The report concludes that environmental tobacco smoke is not a primary lung carcinogen. Critical evaluation of the report, however, shows that this conclusion is not justified. Results of recent epidemiologic studies support the earlier conclusion of the American Environmental Protection Agency (EPA) that environmental tobacco smoke does cause lung cancer. Furthermore, the working group fails to present compelling evidence that the results of the epidemiological studies in this field can be explained by bias or confounding, or that the association between environmental tobacco smoke and lung cancer is biologically implausible. Therefore, we see no reason to modify the conclusion of the EPA that passive smoking causes lung cancer.

摘要

最近,一个由六位欧洲科学家组成的工作小组发表了一份关于接触环境烟草烟雾与肺癌风险的报告。该报告得出结论称,环境烟草烟雾不是主要的肺癌致癌物。然而,对该报告的批判性评估表明,这一结论是不合理的。近期流行病学研究结果支持了美国环境保护局(EPA)较早前得出的结论,即环境烟草烟雾确实会导致肺癌。此外,该工作小组未能提供令人信服的证据,证明该领域流行病学研究结果可由偏差或混杂因素来解释,或者证明环境烟草烟雾与肺癌之间的关联在生物学上是不合理的。因此,我们认为没有理由修改美国环境保护局关于被动吸烟会导致肺癌的结论。

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