Skogsdal Y, Eriksson M, Schollin J
Department of Paediatrics, Orebro Medical Centre Hospital, Sweden.
Acta Paediatr. 1997 Feb;86(2):217-20. doi: 10.1111/j.1651-2227.1997.tb08872.x.
There is evidence that newborn babies feel pain even at the lowest gestational ages when they can survive. Because sweet solutions such as sucrose, given orally, may relieve pain in neonates, we decided to compare the effects of two concentrations of glucose (normally used for intravenous infusions) and of breast milk in a randomized controlled trial in 120 babies requiring heel-prick tests. Glucose solutions and breast milk are readily available in the neonatal department. No other treatment was given. Our results strongly suggest that 1 ml of a 30% glucose solution given orally alleviates mild pain significantly and can be used for this purpose in newborns. Breast milk and 10% glucose did not have a similar effect.
有证据表明，即使是能存活的最低孕周的新生儿也会感到疼痛。由于口服蔗糖等甜味溶液可能减轻新生儿的疼痛，我们决定在一项随机对照试验中，比较两种浓度的葡萄糖（通常用于静脉输注）和母乳对120名需要足跟采血检测的婴儿的影响。葡萄糖溶液和母乳在新生儿科很容易获得。未给予其他治疗。我们的结果有力地表明，口服1毫升30%的葡萄糖溶液能显著减轻轻度疼痛，可用于新生儿的这一目的。母乳和10%的葡萄糖没有类似效果。
