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阑尾切除术:当代评估

Appendectomy: a contemporary appraisal.

作者信息

Hale D A, Molloy M, Pearl R H, Schutt D C, Jaques D P

机构信息

Quality Assurance Office, Assistant Secretary of Defense (Health Affairs), Washington, D.C., USA.

出版信息

Ann Surg. 1997 Mar;225(3):252-61. doi: 10.1097/00000658-199703000-00003.

Abstract

OBJECTIVE

The authors present an accurate and comprehensive snapshot of appendicitis and the practice of appendectomy in the 1990s.

METHODS

Appendectomies were performed on 4950 patients in 147 Department of Defense hospitals worldwide over a 12-month period ending January 31, 1993.

RESULTS

The median age was 23 years (range, 6 months to 82 years) with 64% males and 36% females. The patients were assigned a diagnosis of normal appendix in 632 (13%) cases, acute appendicitis in 3286 (66%) cases, and perforated appendicitis in 1032 (21%) cases. There were no differences in perforation and normal appendix rates between those operations performed in teaching hospitals versus community hospitals or between high-volume hospitals (> or = 100 appendectomies/year) versus low-volume hospitals. Both a preoperative temperature > or = 100.5 and a preoperative leukocyte count > or = 10,000 were incapable of discriminating between patients with appendicitis and those with a normal appendix. Multivariate analysis showed a significantly increased risk of perforation associated with age younger than or equal to 8 years (38% vs. 18%) and age older than or equal to 45 years (49% vs. 18%). Females had a significantly higher rate of normal appendices (19% vs. 9%) and a lower rate of perforation (18% vs. 23%). The complication rates to include reoperation and intraabdominal sepsis were markedly increased in those patients with perforation. There were four deaths in this series (0.08%).

CONCLUSIONS

Despite a marked decline in associated mortality over the past 50 years, rates of perforation and negative appendectomy remain unchanged because they are influenced strongly by factors untouched by the intervening technologic advances.

摘要

目的

作者呈现了20世纪90年代阑尾炎及阑尾切除术的准确而全面的概况。

方法

在截至1993年1月31日的12个月期间,全球147家国防部医院对4950例患者实施了阑尾切除术。

结果

患者的中位年龄为23岁(范围为6个月至82岁),男性占64%,女性占36%。632例(13%)患者被诊断为阑尾正常,3286例(66%)为急性阑尾炎,1032例(21%)为穿孔性阑尾炎。教学医院与社区医院进行的手术之间,以及高容量医院(每年≥100例阑尾切除术)与低容量医院之间,穿孔率和阑尾正常率没有差异。术前体温≥100.5华氏度和术前白细胞计数≥10000都无法区分阑尾炎患者和阑尾正常的患者。多变量分析显示,年龄小于或等于8岁(38%对18%)和年龄大于或等于45岁(49%对18%)的患者穿孔风险显著增加。女性阑尾正常的比例显著更高(19%对9%),穿孔率更低(18%对23%)。穿孔患者的再手术和腹腔内感染等并发症发生率明显增加。该系列中有4例死亡(0.08%)。

结论

尽管在过去50年中相关死亡率显著下降,但穿孔率和阴性阑尾切除术的发生率保持不变,因为它们受到技术进步未触及的因素的强烈影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a29b/1190674/6a4359484f76/annsurg00025-0022-a.jpg

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