人参皂苷对雄性生育能力的影响。
Effects of Panax Ginseng C.A. Meyer saponins on male fertility.
作者信息
Salvati G, Genovesi G, Marcellini L, Paolini P, De Nuccio I, Pepe M, Re M
机构信息
V Clinica Medica, University of Rome La Sapienza, Italy.
出版信息
Panminerva Med. 1996 Dec;38(4):249-54.
Sixty-six patients have been treated with Panax Ginseng C.A. Meyer extract, of whom 30 oligoastenospermic sine causa (group A), 16 oligoastenospermic with idiopathic varicocele (group B). Twenty age-matched volunteers were used as controls (group C). Use of Panax Ginseng extract showed an increase in spermatozoa number/ml and progressive oscillating motility, an increase in plasma total and free testosterone, DHT, FSH and LH levels, but a decrease in mean PRL. It is suggested that ginsenosides may have an effect at different levels of the hypothalamus-pituitary-testis axis.
66例患者接受了人参提取物治疗，其中30例为不明原因的少精子症患者（A组），16例为特发性精索静脉曲张导致的少精子症患者（B组）。选取20名年龄匹配的志愿者作为对照（C组）。使用人参提取物后，每毫升精液中的精子数量及进行性摆动活力增加，血浆总睾酮、游离睾酮、双氢睾酮、促卵泡生成素和促黄体生成素水平升高，但泌乳素平均水平降低。提示人参皂苷可能在下丘脑-垂体-睾丸轴的不同水平发挥作用。
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