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犬瘟热:狮子和老虎的一种常见疾病。

Distemper: not a new disease in lions and tigers.

作者信息

Myers D L, Zurbriggen A, Lutz H, Pospischil A

机构信息

Department of Veterinary Pathology, University of Zurich, Switzerland.

出版信息

Clin Diagn Lab Immunol. 1997 Mar;4(2):180-4. doi: 10.1128/cdli.4.2.180-184.1997.

Abstract

In light of recent canine distemper virus (CDV) epidemics, we set out to determine the historical significance of CDV infection in captive lions and tigers in Switzerland. The retrospective case material consisted of 42 lion and tiger necropsy cases from 1972 to 1992. Necropsy reports for all lions and tigers were reviewed. All existing paraffin tissues were immunohistochemically examined with a polyclonal antibody raised against CDV. The results for 19 of the 42 lions and tigers were classified as positive by immunohistochemistry; 23 results were negative or questionable. The results for four animals (three positive and one negative ) were further tested by in situ hybridization, and the results concurred with the immunohistochemistry findings. CDV infection of large cats is older and more widespread than previously thought. All large cats in captivity should be immunized even if canine distemper is not believed to be a problem for large cats in the area.

摘要

鉴于近期犬瘟热病毒(CDV)的流行情况,我们着手确定瑞士圈养狮子和老虎感染CDV的历史意义。回顾性病例资料包括1972年至1992年的42例狮子和老虎尸检病例。对所有狮子和老虎的尸检报告进行了审查。所有现有的石蜡组织都用针对CDV的多克隆抗体进行了免疫组织化学检查。42只狮子和老虎中有19只的检测结果通过免疫组织化学被判定为阳性;23只的结果为阴性或存疑。对4只动物(3只阳性和1只阴性)的结果进一步进行了原位杂交检测,结果与免疫组织化学结果一致。大型猫科动物感染CDV的情况比之前认为的更为久远且更为普遍。即使犬瘟热不被认为是该地区大型猫科动物的问题,所有圈养的大型猫科动物都应该进行免疫接种。

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Clin Diagn Lab Immunol. 1997 Mar;4(2):180-4. doi: 10.1128/cdli.4.2.180-184.1997.

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